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IL-5 Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7617344

MBS7617344 is a recombinant protein targeting IL-5. Also known as Recombinant Mouse IL-5. Host: HEK293 cells. More details

$590 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL-5, Recombinant Protein
Full Product Name
Recombinant Mouse IL-5
Product Gene Name
IL-5 recombinant protein
Product Synonym Names
EDF; IL 5; IL5; IL-5; Interleukin 5; T cell replacing factor
Host
HEK293 cells
Form/Format
Lyophilized from a 0.2 um filtered solution in 10 mM Hepes, 500 mM NaCl with 5% trehalose, pH7.4
Purity/Purification
Greater than 95% as determined by SDS-PAGE
Preparation and Storage
The lyophilized protein is stable at -20 degree C for up to 1 year, the protein solution can be stored at 2-8 degree C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing 0.1% BSA (make sure BSA will NOT interfere with your experiment) and store in working aliquots at -20 degree C to -80 degree C for 6 months. Avoid repeated freeze/thaw cycle.
Molecular Weight
15,410 Da
Sequence Positions
21-133
3D Structure
ModBase 3D Structure for P04401
Species
Mouse
Tag
C-terminal His
Reconstitution
Centrifuge the vial prior to opening, reconstitute in sterile distilled water or buffer of interest to concentration of 0.1-1mg/ml by gently pipetting 2-3 times, don't vortex
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for IL-5 recombinant protein
Western Blot (WB), ELISA (EIA)

Other Notes

Small volumes of IL-5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-5. It may not necessarily be applicable to this product.

NCBI GI #
6754336
NCBI GeneID
16191
NCBI Accession #
NP_034688.1
UniProt Primary Accession #
P04401
UniProt Related Accession #
P04401
GenBank Nucleotide #
NM_010558.1
NCBI Official Full Name
interleukin-5
NCBI Official Synonym Full Names
interleukin 5
NCBI Official Symbol
Il5
NCBI Official Synonym Symbols
Il-5
UniProt Protein Name
Interleukin-5
UniProt Synonym Protein Names
B-cell growth factor II; BCGF-II; Cytotoxic T-lymphocyte inducer; Eosinophil differentiation factor; T-cell replacing factor; TRF
UniProt Gene Name
Il5
UniProt Synonym Gene Names
Il-5; IL-5; BCGF-II; TRF
UniProt Entry Name
IL5_MOUSE
NCBI Protein Information
interleukin-5; B-cell growth factor II; BCGF-II; T-cell replacing factor; TRF; cytotoxic T-lymphocyte inducer; eosinophil differentiation factor

UniProt Comments for IL-5

IL5: Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. Belongs to the IL-5 family.

Protein type: Secreted, signal peptide; Cytokine; Secreted

Cellular Component: extracellular space; extracellular region

Molecular Function: interleukin-5 receptor binding; growth factor activity; cytokine activity

Biological Process: positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of transcription, DNA-dependent; cytokine and chemokine mediated signaling pathway; positive regulation of cell proliferation; positive regulation of B cell proliferation; positive regulation of JAK-STAT cascade; immune response; positive regulation of transcription factor activity; positive regulation of immunoglobulin secretion; positive regulation of eosinophil differentiation
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Research Articles on IL-5

1. In mice, low-dose IL-2-anti-IL-2 antibody complexes drove group 2 innate lymphoid cells (ILC2) to produce IL-5 and proliferate.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with IL-5 recombinant protein

 Products by Pathway  Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response (BioCarta) Pathway antibodies  Cytokines And Inflammatory Response (BioCarta) Pathway Diagram

Diseases associated with IL-5 recombinant protein

 Disease Name  Pubmed Publications
 Hypersensitivity Antibodies  >133 publications with IL-5 and Hypersensitivity
 Asthma Antibodies  >114 publications with IL-5 and Asthma
 Inflammation Antibodies  >111 publications with IL-5 and Inflammation
 Lung Diseases Antibodies  >88 publications with IL-5 and Lung Diseases
 Eosinophilia Antibodies  >71 publications with IL-5 and Eosinophilia
 Necrosis Antibodies  >61 publications with IL-5 and Necrosis
 Drug Hypersensitivity Antibodies  >18 publications with IL-5 and Drug Hypersensitivity
 Bronchial Hyperreactivity Antibodies  >13 publications with IL-5 and Bronchial Hyperreactivity
 Fibrosis Antibodies  >13 publications with IL-5 and Fibrosis
 Hyperplasia Antibodies  >10 publications with IL-5 and Hyperplasia

Organs/Tissues associated with IL-5 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >343 publications with IL-5 and Blood
 Spleen Antibodies  >29 publications with IL-5 and Spleen
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