Baculovirus IL7 Recombinant Protein – Cat# MBS206449

IL7 Baculovirus Recombinant Protein

Name: IL7 Recombinant Protein; Baculovirus; MyBioSource
Brand: MyBioSource
SKU: MBS206449
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS206449

IL7, as known as interleukin-7 isoform 1, is a cytokine of the hemopoietin family that plays important roles in lymphocyte differentiation, proliferation, and survival. This protein is a hematopoietic growth factor secreted by stromal cells in the bone marrow… More details

$245 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IL7, Recombinant Protein

Full Product Name

IL7, 26-177aa, Human, His-tag, Baculovirus

Product Gene Name

IL7 recombinant protein

Product Synonym Names

Interleukin-7 isoform 1; IL7; IL-7; Il7; Interleukin-7; hlb368

Sequence

ADPDCDIEGK DGKQYESVLM VSIDQLLDSM KEIGSNCLNN EFNFFKRHIC DANKEGMFLF RAARKLRQFL KMNSTGDFDL HLLKVSEGTT ILLNCTGQVK GRKPAALGEA QPTKSLEENK SLKEQKKLND LCFLKRLLQE IKTCWNKILM GTKEHHHHHH H

Host

Baculovirus

Form/Format

Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol.

Purity/Purification

> 90% by SDS-PAGE

Concentration

0.5 mg/ml (determined by Absorbance at 280nm) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

18.4kDa (161aa) 18-28kDa (SDS-PAGE under reducing conditions.)

OMIM

J04156 mRNA

3D Structure

ModBase 3D Structure for P13232

Antigen Species

Human

Tag Information

His-tag

Endotoxin Level

< 1.0 EU per 1 microgram of protein (determined by LAL method)

Product Categories/Family for IL7 recombinant protein

Hormones & Cytokines; Immunology

Applications Tested/Suitable for IL7 recombinant protein

SDS-PAGE

Product References and Citations for IL7 recombinant protein

Iolyeva M., et al. (2013) Blood 122:2271-2281.; Younas M., et al. (2013) J. Immunol. 191:3161-3168.

Other Notes

Small volumes of IL7 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL7 purchase

MBS206449 is a recombinant protein targeting IL7. Also known as IL7, 26-177aa, Human, His-tag, Baculovirus. Host: Baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for IL7. It may not necessarily be applicable to this product.

NCBI GI #

4504677

NCBI GeneID

3574

NCBI Accession #

NP_000871

UniProt Primary Accession #

P13232

UniProt Secondary Accession #

Q5FBY5; Q5FBY9; A0N0L3

UniProt Related Accession #

P13232

GenBank Nucleotide #

NM_000880.3

NCBI Official Full Name

interleukin-7 isoform 1

NCBI Official Synonym Full Names

interleukin 7

NCBI Official Symbol

IL7

NCBI Official Synonym Symbols

IL-7

UniProt Protein Name

Interleukin-7

Protein Family

Interleukin

UniProt Gene Name

IL7

UniProt Synonym Gene Names

IL-7

NCBI Protein Information

interleukin-7

NCBI Summary for IL7

The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.[provided by RefSeq, Dec 2010]

UniProt Comments for IL7

Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation.

Research Articles on IL7

1. In this study, authors compared the concentrations of IL-15 and IL-7 in the plasma of MDS patients (n = 20) compared with that in the plasma of healthy controls (n = 20).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IL7 recombinant protein

Reference Product	PubMed Publications
IL7R recombinant protein	>26 publications with IL7 and IL7R
IL2RG recombinant protein	>13 publications with IL7 and IL2RG
JAK3 recombinant protein	>12 publications with IL7 and JAK3
JAK1 recombinant protein	>9 publications with IL7 and JAK1
IL2RA recombinant protein	>8 publications with IL7 and IL2RA
CRLF2 recombinant protein	>6 publications with IL7 and CRLF2
STAT5B recombinant protein	>2 publications with IL7 and STAT5B
STAT5A recombinant protein	>1 publications with IL7 and STAT5A

Pathways associated with IL7 recombinant protein

Products by Pathway	Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokines And Inflammatory Response Pathway antibodies	Cytokines And Inflammatory Response Pathway Diagram
Development And Heterogeneity Of The ILC Family Pathway antibodies	Development And Heterogeneity Of The ILC Family Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
IL-7 Signaling Pathway antibodies	IL-7 Signaling Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Interleukin-7 Signaling Pathway antibodies	Interleukin-7 Signaling Pathway Diagram

Diseases associated with IL7 recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>55 publications with IL7 and Inflammation
Necrosis Antibodies	>31 publications with IL7 and Necrosis
Disease Models, Animal Antibodies	>28 publications with IL7 and Disease Models, Animal
Multiple Sclerosis Antibodies	>27 publications with IL7 and Multiple Sclerosis
Lymphopenia Antibodies	>26 publications with IL7 and Lymphopenia
Death Antibodies	>24 publications with IL7 and Death
Neoplasms, Experimental Antibodies	>17 publications with IL7 and Neoplasms, Experimental
Gastrointestinal Diseases Antibodies	>8 publications with IL7 and Gastrointestinal Diseases
Cell Transformation, Neoplastic Antibodies	>8 publications with IL7 and Cell Transformation, Neoplastic
Breast Neoplasms Antibodies	>7 publications with IL7 and Breast Neoplasms

Organs/Tissues associated with IL7 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>319 publications with IL7 and Blood
Bone Antibodies	>68 publications with IL7 and Bone
Thymus Antibodies	>51 publications with IL7 and Thymus
Lymph Node Antibodies	>23 publications with IL7 and Lymph Node
Skin Antibodies	>18 publications with IL7 and Skin
Liver Antibodies	>18 publications with IL7 and Liver
Brain Antibodies	>14 publications with IL7 and Brain
Spleen Antibodies	>13 publications with IL7 and Spleen
Intestine Antibodies	>10 publications with IL7 and Intestine
Kidney Antibodies	>7 publications with IL7 and Kidney