IL34 Recombinant Protein – Cat# MBS2009009

Interleukin 34 (IL34) Recombinant Protein

Name: IL34 Recombinant Protein; Interleukin 34; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS2009009
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2009009

MBS2009009 is a recombinant protein targeting IL34. Also known as Recombinant Interleukin 34 (IL34). Host: E Coli. More details

$230 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Interleukin 34 (IL34), Recombinant Protein

Full Product Name

Recombinant Interleukin 34 (IL34)

Product Gene Name

IL34 recombinant protein

Sequence

The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSG SEF- NENLEIWTLA QDKECDLTGY LRGKLQYKNR LQYMKHYFPI NYRIAVPYEG VLRVANITRL KAHVSERELR YLWVLVSLNA TESVLDVLLE GHPSWKYLQE VQTLLENVQR SLMDVEIGPH VEAVLSLLST PGLSLKLVRP KALLDNCFRV MELLYCSCCK QSPILKWQDC ELPRLHPHSP ESLMQCAATN VYPLPRQPPT SLPRSPSSNH GPLP

Host

E Coli

Form/Format

Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.

Purity/Purification

> 95%

Preparation and Storage

Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

Matching Pairs

Unconjugated Antibody: IL34 (MBS2001373)
Immunogen: IL34 (MBS2009009)

Matching Pairs

APC-CY7 Conjugated Antibody: IL34 (MBS2061947)
Immunogen: IL34 (MBS2009009)

Molecular Weight

26.1kDa

Chromosome Location

Chromosome: 19; NC_005118.3 (51680005..51729266). Location: 19q12

3D Structure

ModBase 3D Structure for Q4KM46

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Organism

Rattus norvegicus (Rat)

Expression System

Prokaryotic expression

Residues

Asn21~Pro234 (Accession # Q4KM46) with N-terminal His-Tag

Subcellular Location

Secreted

Endotoxin Level

<1.0EU per 1ug (determined by the LAL method)

Predicted Isoelectric Point

7.7

Reconstitution

Reconstitute in sterile PBS, pH7.2-pH7.4.

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Applications Tested/Suitable for IL34 recombinant protein

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

Other Notes

Small volumes of IL34 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL34. It may not necessarily be applicable to this product.

NCBI GI #

71043738

NCBI GeneID

498951

NCBI Accession #

NP_001020937.1

UniProt Primary Accession #

Q4KM46

UniProt Related Accession #

Q4KM46

GenBank Nucleotide #

NM_001025766.1

NCBI Official Full Name

interleukin-34

NCBI Official Synonym Full Names

interleukin 34

NCBI Official Symbol

Il34

UniProt Protein Name

Interleukin-34

Protein Family

Interleukin

UniProt Gene Name

Il34

UniProt Synonym Gene Names

IL-34

UniProt Entry Name

IL34_RAT

NCBI Protein Information

interleukin-34; IL-34

UniProt Comments for IL34

Function: Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1

By similarity.

Subunit structure: Homodimer. Interacts with CSF1R

By similarity.

Subcellular location: Secreted

By similarity.

Sequence similarities: Belongs to the IL-34 family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with IL34 recombinant protein

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>1 publications with IL34 and Muscle
Brain Antibodies	>1 publications with IL34 and Brain