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ITIH2 Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1573556

MBS1573556 is a recombinant protein targeting ITIH2. Also known as Recombinant Human ITIH2, N-His. Host: E coli. More details

$435 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ITIH2, Recombinant Protein
Full Product Name
Recombinant Human ITIH2, N-His
Product Gene Name
Product Synonym Names
SHAP; ITI heavy chain H2; Serum-derived hyaluronan-associated protein; ITI-HC2; Inter-alpha-trypsin inhibitor complex component II; Inter-alpha-inhibitor heavy chain 2; ITIH2; Inter-alpha-trypsin inhibitor heavy chain H2; IGHEP2
Host
E coli
Form/Format
Lyophilized from a solution in PBS pH7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Purity/Purification
>90% as determined by SDS-PAGE
Preparation and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 degree C for one week. Store at -20 to -80 degree C for twelve months from the date of receipt.
Molecular Weight
106,463 Da
Sequence Positions
Gly452-Asp702
Chromosome Location
Chromosome: 10; NC_000010.10 (7745236..7791483). Location: 10p15
OMIM
146640
3D Structure
ModBase 3D Structure for P19823
Species
Human
Reconstitution
Reconstitute in sterile water for a stock solution.

Product Categories/Family for ITIH2 recombinant protein

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for ITIH2 recombinant protein
SDS-PAGE (SDS), Western Blot (WB), ELISA (EIA), Immunogen

Other Notes

Small volumes of ITIH2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ITIH2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
inter-alpha-trypsin inhibitor heavy chain H2
NCBI Official Synonym Full Names
inter-alpha-trypsin inhibitor heavy chain 2
NCBI Official Symbol
ITIH2
NCBI Official Synonym Symbols
H2P; SHAP
UniProt Protein Name
Inter-alpha-trypsin inhibitor heavy chain H2
UniProt Synonym Protein Names
Inter-alpha-trypsin inhibitor complex component II; Serum-derived hyaluronan-associated protein
UniProt Gene Name
ITIH2
UniProt Synonym Gene Names
IGHEP2; ITI heavy chain H2; ITI-HC2; Inter-alpha-inhibitor heavy chain 2; SHAP
UniProt Entry Name
ITIH2_HUMAN
NCBI Protein Information
inter-alpha-trypsin inhibitor heavy chain H2; ITI-HC2; ITI heavy chain H2; inter-alpha (globulin) inhibitor H2; inter-alpha-inhibitor heavy chain 2; serum-derived hyaluronan-associated protein; inter-alpha (globulin) inhibitor, H2 polypeptide; inter-alpha

NCBI Summary for ITIH2

The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987 [PubMed 2446322]; Himmelfarb et al., 2004 [PubMed 14744536]).[supplied by OMIM, Nov 2009]
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UniProt Comments for ITIH2

ITIH2: May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. Belongs to the ITIH family.

Protein type: Secreted, signal peptide; Inhibitor; Secreted

Chromosomal Location of Human Ortholog: 10p15

Cellular Component: extracellular region

Molecular Function: serine-type endopeptidase inhibitor activity; endopeptidase inhibitor activity

Biological Process: hyaluronan metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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