Human KCNK9 Recombinant Protein – Cat# MBS189008

Figure 1. Human KCNK9 Protein, hFc Tag on SDS-PAGE under reducing condition.

KCNK9 Human Recombinant Protein

Name: KCNK9 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS189008
Price: 280 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS189008

Recombinant Human KCNK9 with C-terminal human Fc tagThis gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have… More details

$280 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

KCNK9, Recombinant Protein

Full Product Name

Human KCNK9 Protein, hFc Tag

Product Gene Name

KCNK9 recombinant protein

Product Synonym Names

K2p9.1; KT3.2; TASK-3; TASK3

Host

HEK293

Form/Format

Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

Purity/Purification

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Preparation and Storage

Store at -20 degree C to -80 degree C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80 degree C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Molecular Weight

42,264 Da

3D Structure

ModBase 3D Structure for Q9NPC2

Tag

C-Human Fc tag

Product Categories/Family for KCNK9 recombinant protein

Bioactive Protein

Other Notes

Small volumes of KCNK9 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KCNK9 purchase

MBS189008 is a recombinant protein targeting KCNK9. Also known as Human KCNK9 Protein, hFc Tag. Host: HEK293.

Additional Details

NCBI/Uniprot data below describe general gene information for KCNK9. It may not necessarily be applicable to this product.

NCBI GI #

542133161

NCBI GeneID

51305

NCBI Accession #

NP_001269463.1

UniProt Primary Accession #

Q9NPC2

UniProt Secondary Accession #

Q2M290; Q540F2

UniProt Related Accession #

Q9NPC2

GenBank Nucleotide #

NM_001282534.1

NCBI Official Full Name

potassium channel subfamily K member 9

NCBI Official Synonym Full Names

potassium two pore domain channel subfamily K member 9

NCBI Official Symbol

KCNK9

NCBI Official Synonym Symbols

KT3.2; TASK3; K2p9.1; TASK-3

UniProt Protein Name

Potassium channel subfamily K member 9

UniProt Synonym Protein Names

Acid-sensitive potassium channel protein TASK-3; TWIK-related acid-sensitive K(+) channel 3; Two pore potassium channel KT3.2; Two pore K(+) channel KT3.2

Protein Family

Potassium channel subfamily

UniProt Gene Name

KCNK9

UniProt Synonym Gene Names

TASK3; Two pore K(+) channel KT3.2

NCBI Protein Information

potassium channel subfamily K member 9

NCBI Summary for KCNK9

This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel dysmorphism syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]

UniProt Comments for KCNK9

pH-dependent, voltage-insensitive, background potassium channel protein.

Research Articles on KCNK9

1. observations implicate TASK-3 as a critical factor in cell cycle progression and corroborate its potential as a therapeutic target in breast cancer treatment.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with KCNK9 recombinant protein

Reference Product	PubMed Publications
KCNS1 recombinant protein	>1 publications with KCNK9 and KCNS1

Pathways associated with KCNK9 recombinant protein

Products by Pathway	Pathway Diagram
Neuronal System Pathway antibodies	Neuronal System Pathway Diagram
Nicotine Activity On Dopaminergic Neurons Pathway antibodies	Nicotine Activity On Dopaminergic Neurons Pathway Diagram
Potassium Channels Pathway antibodies	Potassium Channels Pathway Diagram
TWIK-releated Acid-sensitive K+ Channel (TASK) Pathway antibodies	TWIK-releated Acid-sensitive K+ Channel (TASK) Pathway Diagram
Tandem Pore Domain Potassium Channels Pathway antibodies	Tandem Pore Domain Potassium Channels Pathway Diagram

Diseases associated with KCNK9 recombinant protein

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>12 publications with KCNK9 and Brain Diseases
Acidosis Antibodies	>6 publications with KCNK9 and Acidosis
Cardiovascular Diseases Antibodies	>4 publications with KCNK9 and Cardiovascular Diseases
Hypertension Antibodies	>4 publications with KCNK9 and Hypertension
Inflammation Antibodies	>3 publications with KCNK9 and Inflammation
Heart Diseases Antibodies	>2 publications with KCNK9 and Heart Diseases
Seizures Antibodies	>2 publications with KCNK9 and Seizures
Epilepsy, Absence Antibodies	>2 publications with KCNK9 and Epilepsy, Absence
Birk-Barel Mental Retardation Dysmorphism Syndrome Antibodies	>2 publications with KCNK9 and Birk-Barel Mental Retardation Dysmorphism Syndrome
Respiratory Tract Diseases Antibodies	>1 publications with KCNK9 and Respiratory Tract Diseases

Organs/Tissues associated with KCNK9 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>54 publications with KCNK9 and Brain