Mouse MMP9 Recombinant Protein – Cat# MBS2581441

MMP9 Mouse Recombinant Protein

Name: MMP9 Recombinant Protein; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS2581441
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2581441

Matrix metalloproteinases (MMPs) are neutral proteinases that are involved in the breakdown and remodeling of the extracellular matrix (ECM) under a variety of physiological and pathological conditions, such as morphogenesis, differentiation, angiogenesis and… More details

$235 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MMP9, Recombinant Protein

Full Product Name

Recombinant Mouse MMP9 protein (His tag)

Product Gene Name

MMP9 recombinant protein

Product Synonym Names

92 kDa gelatinase; 92 kDa type IV collagenase; GELB; Gelatinase B; MMP-9; Matrix metalloproteinase-9

Sequence

Met1-Pro73 0

Host

HEK293 Cells

Form/Format

Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Purity/Purification

>95% as determined by reducing SDS-PAGE.

Preparation and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 degree C. Reconstituted protein solution can be stored at 4-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.

Molecular Weight

80,535 Da

3D Structure

ModBase 3D Structure for P41245

Species

Mouse

Tag

C-His

Endotoxin

<1.0EU/mg of the protein as determined by the LAL method.

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5mg/mL. Concentration is measured by UV-Vis.

Product Categories/Family for MMP9 recombinant protein

Proteins; Recombinant Proteins; Others; Cancer; Cardiovascular; Cell Biology

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of MMP9 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MMP9 purchase

MBS2581441 is a recombinant protein targeting MMP9. Also known as Recombinant Mouse MMP9 protein (His tag). Host: HEK293 Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for MMP9. It may not necessarily be applicable to this product.

NCBI GI #

341940960

NCBI GeneID

17395

NCBI Accession #

P41245.2

UniProt Primary Accession #

P41245

UniProt Secondary Accession #

Q06788; Q80XI8; Q9DC02

UniProt Related Accession #

P41245

NCBI Official Full Name

Matrix metalloproteinase-9

NCBI Official Synonym Full Names

matrix metallopeptidase 9

NCBI Official Symbol

Mmp9

NCBI Official Synonym Symbols

Clg4b; MMP-9; B/MMP9; AW743869; pro-MMP-9

UniProt Protein Name

Matrix metalloproteinase-9

UniProt Synonym Protein Names

92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELB

Protein Family

Matrix metalloproteinase

UniProt Gene Name

Mmp9

UniProt Synonym Gene Names

Clg4b; MMP-9; GELB

UniProt Entry Name

MMP9_MOUSE

NCBI Protein Information

matrix metalloproteinase-9; GELB; Gel B; gelatinase B; 92kD gelatinase; 92kDa gelatinase; 92 kDa gelatinase; collagenase type IVB; 92kD type IV collagenase; 92kDa type IV collagenase; 92 kDa type IV collagenase; matrix metalloproteinase 9

UniProt Comments for MMP9

MMP9: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. Exists as monomer or homodimer; disulfide-linked. Exists also as heterodimer with a 25 kDa protein. Macrophages and transformed cell lines produce only the monomeric form. Interacts with ECM1. Activated by 4-aminophenylmercuric acetate and phorbol ester. Up-regulated by ARHGEF4, SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. Produced by normal alveolar macrophages and granulocytes. Inhibited by histatin-3 1/24 (histatin-5). Inhibited by ECM1. Belongs to the peptidase M10A family.

Protein type: Protease; Secreted; Motility/polarity/chemotaxis; EC 3.4.24.35; Secreted, signal peptide

Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; protein complex; extracellular region

Molecular Function: peptidase activity; identical protein binding; zinc ion binding; hydrolase activity; metallopeptidase activity; fibronectin binding; metal ion binding; metalloendopeptidase activity; endopeptidase activity; protein complex binding

Biological Process: positive regulation of keratinocyte migration; response to drug; ossification; extracellular matrix organization and biogenesis; positive regulation of apoptosis; positive regulation of leukocyte migration; tissue remodeling; positive regulation of synaptic plasticity; proteolysis; protein oligomerization; collagen catabolic process; positive regulation of angiogenesis; negative regulation of fibroblast proliferation; response to oxidative stress; leukocyte migration; skeletal development; embryo implantation; transformation of host cell by virus

Research Articles on MMP9

1. TNF-alpha-induced MMP-9 expression is mediated through a c-Src-dependent PDGFR transactivation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with MMP9 recombinant protein

Products by Pathway	Pathway Diagram
Activation Of Matrix Metalloproteinases Pathway antibodies	Activation Of Matrix Metalloproteinases Pathway Diagram
Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies	Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Bladder Cancer Pathway antibodies	Bladder Cancer Pathway Diagram
Bladder Cancer Pathway antibodies	Bladder Cancer Pathway Diagram
Collagen Degradation Pathway antibodies	Collagen Degradation Pathway Diagram
Collagen Formation Pathway antibodies	Collagen Formation Pathway Diagram
Degradation Of The Extracellular Matrix Pathway antibodies	Degradation Of The Extracellular Matrix Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
EPH-Ephrin Signaling Pathway antibodies	EPH-Ephrin Signaling Pathway Diagram

Diseases associated with MMP9 recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>497 publications with MMP9 and Inflammation
Neoplasm Invasiveness Antibodies	>403 publications with MMP9 and Neoplasm Invasiveness
Neoplasm Metastasis Antibodies	>355 publications with MMP9 and Neoplasm Metastasis
Breast Neoplasms Antibodies	>166 publications with MMP9 and Breast Neoplasms
Liver Diseases Antibodies	>148 publications with MMP9 and Liver Diseases
Aortic Diseases Antibodies	>98 publications with MMP9 and Aortic Diseases
Carcinoma, Squamous Cell Antibodies	>96 publications with MMP9 and Carcinoma, Squamous Cell
Aortic Aneurysm Antibodies	>93 publications with MMP9 and Aortic Aneurysm
Aortic Aneurysm, Abdominal Antibodies	>76 publications with MMP9 and Aortic Aneurysm, Abdominal
Carcinoma, Hepatocellular Antibodies	>72 publications with MMP9 and Carcinoma, Hepatocellular

Organs/Tissues associated with MMP9 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>810 publications with MMP9 and Blood
Lung Antibodies	>356 publications with MMP9 and Lung
Bone Antibodies	>319 publications with MMP9 and Bone
Brain Antibodies	>265 publications with MMP9 and Brain
Liver Antibodies	>211 publications with MMP9 and Liver
Heart Antibodies	>204 publications with MMP9 and Heart
Bone Marrow Antibodies	>135 publications with MMP9 and Bone Marrow
Skin Antibodies	>118 publications with MMP9 and Skin
Embryonic Tissue Antibodies	>111 publications with MMP9 and Embryonic Tissue
Eye Antibodies	>85 publications with MMP9 and Eye