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MuTED Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS204621

Muted homolog, also known as MuTED, is involved in the development of lysosome related organelles, such as melanosomes and platelet dense granules. MuTED interacts with pallidin, dystrobrevin binding protein 1 and CNO/cappuccino. It is part of the biogenesis… More details

$230 / 0.004 mg +1 FREE 8GB USB
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MuTED, Recombinant Protein
Full Product Name
MuTED, 1-187aa, Human, His tag, E Coli
Product Gene Name
Product Synonym Names
Muted homolog; Mu
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMSGGGTE TPVGCEAAPG GGSKKRDSLG TAGSAHLIIK DLGEIHSRLL DHRPVIQGET RYFVKEFEEK RGLREMRVLE NLKNMIHETN EHTLPKCRDT MRDSLSQVLQ RLQAANDSVC RLQQREQERK KIHSDHLVAS EKQHMLQWDN FMKEQPNKRA EVDEEHRKAM ERLKEQYAEM EKDLAKFSTF
Host
E Coli
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.1M NaCl, 40% glycerol, 2mM DTT, 0.1mM PMSF, 1mM EDTA
Purity/Purification
> 90% by SDS-PAGE
Concentration
0.25 mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
24 kDa (210aa), confirmed by MALDI-TOF
OMIM
AF426434 mRNA
3D Structure
ModBase 3D Structure for Q8TDH9
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for MuTED recombinant protein

Applications Tested/Suitable for MuTED recombinant protein
SDS-PAGE

Product References and Citations for MuTED recombinant protein

Ciciotte S L., et al. (2003) Blood. 101: 4402-4407; Starcevic M., et al. (2004) J Biol Chem. 279: 28393-28401.

Other Notes

Small volumes of MuTED recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MuTED purchase

MBS204621 is a recombinant protein targeting MuTED. Also known as MuTED, 1-187aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for MuTED. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
biogenesis of lysosome-related organelles complex 1 subunit 5 isoform 1
NCBI Official Synonym Full Names
biogenesis of lysosomal organelles complex 1 subunit 5
NCBI Official Symbol
BLOC1S5
NCBI Official Synonym Symbols
MU; BLOS5; MUTED
UniProt Protein Name
Biogenesis of lysosome-related organelles complex 1 subunit 5
UniProt Synonym Protein Names
Protein Muted homolog
UniProt Gene Name
BLOC1S5
UniProt Synonym Gene Names
MUTED; BLOC-1 subunit 5
NCBI Protein Information
biogenesis of lysosome-related organelles complex 1 subunit 5

NCBI Summary for MuTED

This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene. [provided by RefSeq, Dec 2010]
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UniProt Comments for MuTED

Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MuTED recombinant protein

 Reference Product  PubMed Publications
 DTNBP1 recombinant protein  >2 publications with MuTED and DTNBP1

Diseases associated with MuTED recombinant protein

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