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NGF Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2581024

Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, alpha, beta, and gamma, among which,… More details

$235 / 0.02 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Ngf, Recombinant Protein
Full Product Name
Recombinant Rat Ngf protein (His tag)
Product Gene Name
Ngf recombinant protein
Product Synonym Names
Beta nerve growth factor precursor; HSAN5; MGC161426; NGFB; NGFBMGC161428; beta subunit; beta-NGF; beta-nerve growth factor; betaNGF; nerve growth factor; nerve growth factor (beta polypeptide)
Sequence
Ser122-Gly 241
Host
E coli
Form/Format
Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Preparation and Storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 degree C. Reconstituted protein solution can be stored at 4-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Molecular Weight
27,010 Da
3D Structure
ModBase 3D Structure for P25427
Species
Rat
Tag
N-His
Endotoxin
<10EU/mg of the protein as determined by the LAL method.
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5mg/mL. Concentration is measured by UV-Vis.

Product Categories/Family for Ngf recombinant protein

Proteins; Recombinant Proteins; Others; Cancer; Neuroscience
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Ngf recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ngf purchase

MBS2581024 is a recombinant protein targeting Ngf. Also known as Recombinant Rat Ngf protein (His tag). Host: E coli.

Additional Details

NCBI/Uniprot data below describe general gene information for Ngf. It may not necessarily be applicable to this product.

NCBI GI #
1352495
NCBI GeneID
310738
NCBI Accession #
P25427.2
UniProt Primary Accession #
P25427
UniProt Related Accession #
P25427
NCBI Official Full Name
Beta-nerve growth factor
NCBI Official Synonym Full Names
nerve growth factor (beta polypeptide)
NCBI Official Symbol
Ngf
NCBI Official Synonym Symbols
Ngfb; beta-NGF
UniProt Protein Name
Beta-nerve growth factor
Protein Family
Beta-nerve growth factor
UniProt Gene Name
Ngf
UniProt Synonym Gene Names
Ngfb; Beta-NGF
UniProt Entry Name
NGF_RAT
NCBI Protein Information
beta-nerve growth factor

UniProt Comments for Ngf

Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI.
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Research Articles on Ngf

1. NGF played an important role in the activation of Akt and subsequent up-regulation of BDNF in the sensory neurons in visceral inflammation such as cystitis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Ngf recombinant protein

 Reference Product  PubMed Publications
 Ntrk1 recombinant protein  >2001 publications with Ngf and Ntrk1
 Ntrk2 recombinant protein  >502 publications with Ngf and Ntrk2
 Ngfr recombinant protein  >239 publications with Ngf and Ngfr
 Casp3 recombinant protein  >173 publications with Ngf and Casp3
 Shc1 recombinant protein  >26 publications with Ngf and Shc1
 Mapk8 recombinant protein  >10 publications with Ngf and Mapk8
 Ntf4 recombinant protein  >7 publications with Ngf and Ntf4
 Shc3 recombinant protein  >2 publications with Ngf and Shc3

Pathways associated with Ngf recombinant protein

 Products by Pathway  Pathway Diagram
 ARMS-mediated Activation Pathway antibodies  ARMS-mediated Activation Pathway Diagram
 Activation Of TRKA Receptors Pathway antibodies  Activation Of TRKA Receptors Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Axonal Growth Stimulation Pathway antibodies  Axonal Growth Stimulation Pathway Diagram
 Cell Death Signalling Via NRAGE, NRIF And NADE Pathway antibodies  Cell Death Signalling Via NRAGE, NRIF And NADE Pathway Diagram
 Ceramide Signalling Pathway antibodies  Ceramide Signalling Pathway Diagram
 Frs2-mediated Activation Pathway antibodies  Frs2-mediated Activation Pathway Diagram
 Id Signaling Pathway antibodies  Id Signaling Pathway Diagram
 Inflammatory Mediator Regulation Of TRP Channels Pathway antibodies  Inflammatory Mediator Regulation Of TRP Channels Pathway Diagram

Diseases associated with Ngf recombinant protein

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2164 publications with Ngf and Nervous System Diseases
 Pain Antibodies  >730 publications with Ngf and Pain
 Neurodegenerative Diseases Antibodies  >712 publications with Ngf and Neurodegenerative Diseases
 Inflammation Antibodies  >682 publications with Ngf and Inflammation
 Nerve Degeneration Antibodies  >600 publications with Ngf and Nerve Degeneration
 Peripheral Nervous System Diseases Antibodies  >457 publications with Ngf and Peripheral Nervous System Diseases
 Necrosis Antibodies  >442 publications with Ngf and Necrosis
 Hyperalgesia Antibodies  >309 publications with Ngf and Hyperalgesia
 Heart Diseases Antibodies  >115 publications with Ngf and Heart Diseases
 Neurobehavioral Manifestations Antibodies  >111 publications with Ngf and Neurobehavioral Manifestations

Organs/Tissues associated with Ngf recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >110 publications with Ngf and Connective Tissue
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