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NPPC Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS205456

NPPC is proteolytically processed to form a secreted hormone of the natriuretic peptide family. The hormone regulates the growth and differentiation of cartilaginous growth plate chondrocytes and may also be vasoactive and natriuretic. Recombinant human NPPC… More details

$230 / 0.02 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NPPC, Recombinant Protein
Full Product Name
NPPC, 24-126aa, Human, His tag, E Coli
Product Gene Name
Product Synonym Names
C-type natriuretic peptide; C-type natriuretic peptide; CNP; CNP2
Sequence
MGSSHHHHHH SSGLVPRGSH MGSKPGAPPK VPRTPPAEEL AEPQAAGGGQ KKGDKAPGGG GANLKGDRSR LLRDLRVDTK SRAAWARLLQ EHPNARKYKG ANKKGLSKGC FGLKLDRIGS MSGLGC
Host
E Coli
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol,
Purity/Purification
> 85% by SDS-PAGE
Concentration
0.25 mg/ml (determined by BCA assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
13.2kDa (126aa), confirmed by MALDI-TOF
OMIM
M64710 Genomic DNA
3D Structure
ModBase 3D Structure for P23582
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for NPPC recombinant protein

Applications Tested/Suitable for NPPC recombinant protein
SDS-PAGE

Product References and Citations for NPPC recombinant protein

Thompson,I.R., et al. (2012) Endocr. Relat. Cancer 19 (4), 497-508; Kuehnl,A., et al. (2012) Eur J Vasc Endovasc Surg 43 (6), 649-654;

Other Notes

Small volumes of NPPC recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NPPC purchase

MBS205456 is a recombinant protein targeting NPPC. Also known as NPPC, 24-126aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for NPPC. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
C-type natriuretic peptide preproprotein
NCBI Official Synonym Full Names
natriuretic peptide C
NCBI Official Symbol
NPPC
NCBI Official Synonym Symbols
CNP; CNP2
UniProt Protein Name
C-type natriuretic peptide
UniProt Gene Name
NPPC
UniProt Synonym Gene Names
CNP2
NCBI Protein Information
C-type natriuretic peptide

NCBI Summary for NPPC

This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cardiac natriuretic peptides CNP-53, CNP-29 and CNP-22, which belong to the natriuretic family of peptides. The encoded peptides exhibit vasorelaxation activity in laboratory animals and elevated levels of CNP-22 have been observed in the plasma of chronic heart failure patients. [provided by RefSeq, Oct 2015]
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UniProt Comments for NPPC

Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3 ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with NPPC recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >2 publications with NPPC and Skin
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