RAB14 Recombinant Protein

Name: RAB14 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS204466
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS204466

RAB14 is a member of the RAB protein family, low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane bound organelles. This protein is thought to be involved in vesicular trafficking and neurotransmitter release… More details

$230 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RAB14, Recombinant Protein

Full Product Name

RAB14, 1-215aa, Human, His tag, E Coli

Product Gene Name

RAB14 recombinant protein

Product Synonym Names

Ras-related protein Rab-14; FBP; RAB-14

Sequence

MGSSHHHHHH SSGLVPRGSH MGSMATAPYN YSYIFKYIII GDMGVGKSCL LHQFTEKKFM ADCPHTIGVE FGTRIIEVSG QKIKLQIWDT AGQERFRAVT RSYYRGAAGA LMVYDITRRS TYNHLSSWLT DARNLTNPNT VIILIGNKAD LEAQRDVTYE EAKQFAEENG LLFLEASAKT GENVEDAFLE AAKKIYQNIQ DGSLDLNAAE SGVQHKPSAP QGGRLTSEPQ PQREGCGC

Host

E Coli

Form/Format

Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT

Purity/Purification

90% by SDS-PAGE

Concentration

0.5 mg/ml (determined by Bradford assay) (lot specific)

Preparation and Storage

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Molecular Weight

26.3 kDa (238aa), confirmed by MALDI-TOF

OMIM

AF152463 mRNA

3D Structure

ModBase 3D Structure for P61106

Antigen Species

Human

Tag Information

His-tag

Product Categories/Family for RAB14 recombinant protein

Signal Transduction

Applications Tested/Suitable for RAB14 recombinant protein

SDS-PAGE

Product References and Citations for RAB14 recombinant protein

Junutula JR. et al. (2004) Mol Biol Cell. 15:2218-29.; Olkkonen V.M. et al. (1993) J. Cell Sci. 106:1249-61.

Other Notes

Small volumes of RAB14 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB14 purchase

MBS204466 is a recombinant protein targeting RAB14. Also known as RAB14, 1-215aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB14. It may not necessarily be applicable to this product.

NCBI GI #

19923483

NCBI GeneID

51552

NCBI Accession #

NP_057406

UniProt Primary Accession #

P61106

UniProt Secondary Accession #

P35287; Q5JVD4; Q6Q7K5; Q969L0; Q9UI11; B3KR31

UniProt Related Accession #

P61106

GenBank Nucleotide #

NM_016322.3

NCBI Official Full Name

ras-related protein Rab-14

NCBI Official Synonym Full Names

RAB14, member RAS oncogene family

NCBI Official Symbol

RAB14

NCBI Official Synonym Symbols

FBP; RAB-14

UniProt Protein Name

Ras-related protein Rab-14

Protein Family

Ras-related protein

UniProt Gene Name

RAB14

NCBI Protein Information

ras-related protein Rab-14

NCBI Summary for RAB14

RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004 [PubMed 15004230]).[supplied by OMIM, Mar 2009]

UniProt Comments for RAB14

Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion.

Research Articles on RAB14

1. The results from this analysis indicated that Rab11a, Rab11c(Rab25) and Rab14 were expressed in a wide range of cell lines, including the human placental trophoblastic BeWo cell line.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RAB14 recombinant protein

Reference Product	PubMed Publications
SLC2A4 recombinant protein	>4 publications with RAB14 and SLC2A4
TBC1D4 recombinant protein	>4 publications with RAB14 and TBC1D4
MYO5A recombinant protein	>2 publications with RAB14 and MYO5A
MYO1C recombinant protein	>1 publications with RAB14 and MYO1C

Pathways associated with RAB14 recombinant protein

Products by Pathway	Pathway Diagram
AMPK Signaling Pathway antibodies	AMPK Signaling Pathway Diagram
AMPK Signaling Pathway antibodies	AMPK Signaling Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Membrane Trafficking Pathway antibodies	Membrane Trafficking Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Neutrophil Degranulation Pathway antibodies	Neutrophil Degranulation Pathway Diagram
PI Metabolism Pathway antibodies	PI Metabolism Pathway Diagram

Diseases associated with RAB14 recombinant protein

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>4 publications with RAB14 and Immune System Diseases
Lung Neoplasms Antibodies	>3 publications with RAB14 and Lung Neoplasms
Brain Diseases Antibodies	>1 publications with RAB14 and Brain Diseases
Neoplasms, Experimental Antibodies	>1 publications with RAB14 and Neoplasms, Experimental
Disease Models, Animal Antibodies	>1 publications with RAB14 and Disease Models, Animal
Fibrosis Antibodies	>1 publications with RAB14 and Fibrosis
Kidney Diseases Antibodies	>1 publications with RAB14 and Kidney Diseases

Organs/Tissues associated with RAB14 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>11 publications with RAB14 and Blood
Lung Antibodies	>8 publications with RAB14 and Lung
Muscle Antibodies	>8 publications with RAB14 and Muscle
Kidney Antibodies	>8 publications with RAB14 and Kidney
Brain Antibodies	>6 publications with RAB14 and Brain
Embryonic Tissue Antibodies	>3 publications with RAB14 and Embryonic Tissue
Vascular Antibodies	>3 publications with RAB14 and Vascular
Nerve Antibodies	>3 publications with RAB14 and Nerve
Lymph Antibodies	>2 publications with RAB14 and Lymph
Lymph Node Antibodies	>2 publications with RAB14 and Lymph Node