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SH3GL2 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS204783

SH3GL2 (SH3-domain GRB2-like 2), also known as endophilin-A1, belongs to the endophilin family. It contains a BAR domain and a SH3 domain. Members of the BAR domain protein superfamily are essential elements of cellular traffic. Endophilins are among the best… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SH3GL2, Recombinant Protein
Full Product Name
SH3GL2, 1-352aa, Human, His tag, E Coli
Product Synonym Names
Endophilin-A1; CNSA2; EEN-B1; SH3D2A; SH3P4
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMSVAGL KKQFHKATQK VSEKVGGAEG TKLDDDFKEM ERKVDVTSRA VMEIMTKTIE YLQPNPASRA KLSMINTMSK IRGQEKGPGY PQAEALLAEA MLKFGRELGD DCNFGPALGE VGEAMRELSE VKDSLDIEVK QNFIDPLQNL HDKDLREIQH HLKKLEGRRL DFDYKKKRQG KIPDEELRQA LEKFDESKEI AESSMFNLLE MDIEQVSQLS ALVQAQLEYH KQAVQILQQV TVRLEERIRQ ASSQPRREYQ PKPRMSLEFP TGDSTQPNGG LSHTGTPKPS GVQMDQPCCR ALYDFEPENE GELGFKEGDI ITLTNQIDEN WYEGMLHGHS GFFPINYVEI LVALPH
Host
E Coli
Form/Format
Liquid. In 20 mM Tris-HCl Buffer, pH8.0, 10% glycerol, 1mM DTT, 50mM NaCl
Purity/Purification
> 90% by SDS-PAGE
Concentration
1mg/ml (determined by Bradford assay) (lot specific)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Molecular Weight
42.5 kDa (376aa) confirmed by MALDI-TOF
OMIM
X99657 mRNA
3D Structure
ModBase 3D Structure for Q99962
Antigen Species
Human
Tag Information
His-tag

Product Categories/Family for SH3GL2 recombinant protein

Applications Tested/Suitable for SH3GL2 recombinant protein
SDS-PAGE

Product References and Citations for SH3GL2 recombinant protein

Shang C, Guo Y, Fu S, Fu W, Sun K.; Med Sci Monit. 2010 Jun;16 (6):BR168-73.

Other Notes

Small volumes of SH3GL2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SH3GL2 purchase

MBS204783 is a recombinant protein targeting SH3GL2. Also known as SH3GL2, 1-352aa, Human, His tag, E Coli. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for SH3GL2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
endophilin-A1
NCBI Official Synonym Full Names
SH3 domain containing GRB2 like 2, endophilin A1
NCBI Official Symbol
SH3GL2
NCBI Official Synonym Symbols
CNSA2; SH3P4; EEN-B1; SH3D2A
UniProt Protein Name
Endophilin-A1
UniProt Synonym Protein Names
EEN-B1; Endophilin-1; SH3 domain protein 2A; SH3 domain-containing GRB2-like protein 2
Protein Family
UniProt Gene Name
SH3GL2
UniProt Synonym Gene Names
CNSA2; SH3D2A
NCBI Protein Information
endophilin-A1

UniProt Comments for SH3GL2

Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with SH3GL2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >26 publications with SH3GL2 and Brain
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