Human WDR48 Recombinant Protein – Cat# MBS1577235

SDS PAGE for Recombinant Human WDR48 Protein

WDR48 Human Recombinant Protein

Name: WDR48 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1577235
Price: 435 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1577235

MBS1577235 is a recombinant protein targeting WDR48. Also known as Recombinant Human WDR48 Protein, N-His. Host: E coli. More details

$435 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

WDR48, Recombinant Protein

Full Product Name

Recombinant Human WDR48 Protein, N-His

Product Gene Name

WDR48 recombinant protein

Product Synonym Names

USP1-associated factor 1; WD repeat-containing protein 48; KIAA1449; WDR48; p80; WD repeat endosomal protein; UAF1

Host

E coli

Form/Format

Lyophilized from a solution in PBS pH7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Purity/Purification

>90% as determined by SDS-PAGE

Preparation and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 degree C for one week. Store at -20 to -80 degree C for twelve months from the date of receipt.

Molecular Weight

677

Sequence Positions

Gly32-Lys358

OMIM

612167

3D Structure

ModBase 3D Structure for Q8TAF3

Species

Human

Reconstitution

Reconstitute in sterile water for a stock solution.

Product Categories/Family for WDR48 recombinant protein

Recombinant Proteins

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for WDR48 recombinant protein

SDS-PAGE (SDS), Western Blot (WB), ELISA (EIA), Immunogen

Other Notes

Small volumes of WDR48 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for WDR48. It may not necessarily be applicable to this product.

NCBI GI #

74760390

NCBI GeneID

57599

NCBI Accession #

Q8TAF3.1

UniProt Primary Accession #

Q8TAF3

UniProt Secondary Accession #

Q63HJ2; Q658Y1; Q8N3Z1; Q9NSK8; Q9P279; B4DM86; B4DQI2; B4DY84

UniProt Related Accession #

Q8TAF3

NCBI Official Full Name

WD repeat-containing protein 48

NCBI Official Synonym Full Names

WD repeat domain 48

NCBI Official Symbol

WDR48

NCBI Official Synonym Symbols

P80; UAF1; SPG60

UniProt Protein Name

WD repeat-containing protein 48

UniProt Synonym Protein Names

USP1-associated factor 1; WD repeat endosomal protein; p80

Protein Family

WD repeat-containing protein

UniProt Gene Name

WDR48

UniProt Synonym Gene Names

KIAA1449; UAF1

UniProt Entry Name

WDR48_HUMAN

NCBI Protein Information

WD repeat-containing protein 48; USP1 associated factor 1; USP1-associated factor 1; WD repeat endosomal protein

UniProt Comments for WDR48

WDR48: an ubiquitous lysosomal WD40 repeat protein. May play a role in vesicular transport or membrane fusion events necessary for transport to lysosomes. Induces lysosomal vesicle formation via interaction with Herpesvirus saimiri tyrosine kinase-interacting protein (TIP). Subsequently, TIP recruits tyrosine-protein kinase LCK, resulting in down-regulation of T-cell antigen receptor TCR. May play a role in generation of enlarged endosomal vesicles via interaction with TIP.

Protein type: Ubiquitin conjugating system; Vesicle

Chromosomal Location of Human Ortholog: 3p21.33

Cellular Component: intracellular membrane-bound organelle; lysosome; nucleus

Molecular Function: protein binding

Biological Process: skin development; protein deubiquitination; viral reproduction; skeletal morphogenesis; single fertilization; multicellular organism growth; homeostasis of number of cells; embryonic organ development; spermatogenesis; double-strand break repair via homologous recombination; positive regulation of epithelial cell proliferation

Research Articles on WDR48

1. Coimmunoprecipitation experiments indicated that human papillomavirus type 31 E1 assembles into a ternary complex with UAF1 and any one of these three USPs: USP1, USP12 and USP46.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with WDR48 recombinant protein

Products by Pathway	Pathway Diagram
Fanconi Anemia Pathway antibodies	Fanconi Anemia Pathway Diagram
Fanconi Anemia Pathway antibodies	Fanconi Anemia Pathway Diagram

Organs/Tissues associated with WDR48 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>2 publications with WDR48 and Blood
Lymph Antibodies	>1 publications with WDR48 and Lymph
Prostate Antibodies	>1 publications with WDR48 and Prostate
Eye Antibodies	>1 publications with WDR48 and Eye
Vascular Antibodies	>1 publications with WDR48 and Vascular
Lymph Node Antibodies	>1 publications with WDR48 and Lymph Node
Ovary Antibodies	>1 publications with WDR48 and Ovary