Complement Factor B (CFB) ELISA Kit for Simian

Name: Simian CFB ELISA Kit; Complement Factor B; MyBioSource
Brand: MyBioSource
SKU: MBS9313237
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9313237

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of CFB (hereafter termed "analyte") in undiluted original Simian body fluids, tissue homogenates,… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Complement Factor B (CFB), ELISA Kit

Full Product Name

Simian Complement Factor B (CFB) ELISA Kit

Product Gene Name

CFB elisa kit

Species Reactivity

Simian

Assay Type

Quantitative Sandwich

Samples

Body fluids, tissue homogenates, secretions or feces samples

Detection Range

15.6ug/ml-500ug/ml

Sensitivity

2.0ug/ml.

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Intra-assay Precision

Intra-assay CV (%) is less than 15%

Molecular Weight

85,513 Da

Chromosome Location

Chromosome: 6; NC_006473.3 (32225297..32231135). Location: chromosome: 6

3D Structure

ModBase 3D Structure for Q864W0

Other Notes

Small volumes of CFB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CFB purchase

MBS9313237 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Complement Factor B (CFB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CFB. The ELISA analytical biochemical technique of the MBS9313237 kit is based on CFB antibody-CFB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CFB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CFB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CFB. It may not necessarily be applicable to this product.

NCBI GI #

57114202

NCBI GeneID

494140

NCBI Accession #

NP_001009169.1

UniProt Primary Accession #

Q864W0

UniProt Related Accession #

Q864W0

GenBank Nucleotide #

NM_001009169.1

NCBI Official Full Name

complement factor B

NCBI Official Symbol

CFB

NCBI Official Synonym Symbols

UniProt Protein Name

Complement factor B

UniProt Synonym Protein Names

C3/C5 convertase

Protein Family

Complement factor

UniProt Gene Name

CFB

UniProt Synonym Gene Names

UniProt Entry Name

CFAB_PANTR

NCBI Protein Information

complement factor B; C3/C5 convertase

UniProt Comments for CFB

Function: Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes

By similarity.

Catalytic activity: Cleavage of Arg-|-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg-|-Xaa bond in complement component C5 alpha-chain to yield C5a and C5b.

Subunit structure: Monomer

By similarity.

Subcellular location: Secreted.

Sequence similarities: Belongs to the peptidase S1 family.Contains 1 peptidase S1 domain.Contains 3 Sushi (CCP/SCR) domains.Contains 1 VWFA domain.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CFB elisa kit

Reference Product	PubMed Publications
CFH elisa kit	>81 publications with CFB and CFH
CFD elisa kit	>4 publications with CFB and CFD

Pathways associated with CFB elisa kit

Products by Pathway	Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Staphylococcus Aureus Infection Pathway antibodies	Staphylococcus Aureus Infection Pathway Diagram
Staphylococcus Aureus Infection Pathway antibodies	Staphylococcus Aureus Infection Pathway Diagram

Diseases associated with CFB elisa kit

Disease Name	Pubmed Publications
Macular Degeneration Antibodies	>68 publications with CFB and Macular Degeneration
Macular Degeneration, Age-Related, 1 Antibodies	>36 publications with CFB and Macular Degeneration, Age-Related, 1
Cardiovascular Diseases Antibodies	>17 publications with CFB and Cardiovascular Diseases
Immune System Diseases Antibodies	>16 publications with CFB and Immune System Diseases
Inflammation Antibodies	>15 publications with CFB and Inflammation
Drug Toxicity Antibodies	>15 publications with CFB and Drug Toxicity
Necrosis Antibodies	>13 publications with CFB and Necrosis
Nervous System Diseases Antibodies	>13 publications with CFB and Nervous System Diseases
Neoplasms Antibodies	>12 publications with CFB and Neoplasms
Fibrosis Antibodies	>11 publications with CFB and Fibrosis

Organs/Tissues associated with CFB elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Frontal Lobe Antibodies	>1 publications with CFB and Brain Frontal Lobe