Chemical structure of K252A (SIH-455), a Kinase inhibitor (pan-specific). CAS #: 99533-80-9. Molecular Formula: C27H21N3O5. Molecular Weight: 467.5 g/mol.

K252A Small Molecule

Name: K252A Small Molecule; MyBioSource
Brand: MyBioSource
SKU: MBS808155
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS808155

K252A is a non-selective protein kinase inhibitor that exhibits a wide range of effects. Specifically, it has been seen to inhibit PKA, PKC, PKG, CAM kinase II, mlCK, Ser/Thr kinase, Met, and receptor tyrosine kinases. It has been shown to prevent… More details

$230 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

K252A, Small Molecule

Full Product Name

K252A

Product Gene Name

K252A small molecule

Product Synonym Names

Kinase inhibitor; (9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester

Host

Nonomuraea longicatena

Form/Format

White solid

Purity/Purification

>=98% (HPLC)

Preparation and Storage

Store at -20 degree C.

Molecular Weight

467.5

Solubility

Soluble to 25 mM in DMSO

CAS Number

99533-80-9

Molecular Formula

C27H21N3O5

SMILES

[N]47C1=C(C6=C(C2=C1[N](C3=CC=CC=C23)[C@@H]5O[C@]4(C(C5)(O)C(=O)OC)C)C(NC6)=O)C8=C7C=CC=C8

InChI

1S/C27H21N3O5/c1-26-27(33,25(32)34-2)11-18(35-26)29-16-9-5-3-7-13(16)20-21-15(12-28-24(21)31)19-14-8-4-6-10-17(14)30(26)23(19)22(20)29/h3-10,18,33H,11-12H2,1-2H3,(H,28,31)/t18?,26-,27-/m1/s1

InChI Key

KOZFSFOOLUUIGY-CYBHFKQVSA-N

PubChem CID

11612445

Product Categories/Family for K252A small molecule

Small Molecules; Inhibitor; Cell Signaling; Cancer; Apoptosis; Cancer Growth Inhibitors; Tyrosine Kinase Inhibitors

Product References and Citations for K252A small molecule

1. Morotti A., Mila S., Accorner, P., Tagliabue E., & Ponzetto C. (2002) Oncogene. 21(32): 4885-4893. 2. Hashimoto Y., et al. (1991) Biochem. Biophys. Res. Comm. 181(1): 423-429. 3. Raychaudhuri S.P., Sanyal M., Weltman H., & Kundu-Raychaudhuri S. (2004) J. Invest. Derm. 122(3): 812-819.

Other Notes

Small volumes of K252A small molecule vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for K252A purchase

MBS808155 is a small molecule targeting K252A. Host: Nonomuraea longicatena.