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PYR41 Small Molecule

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS808035

Inhibits ubiquitin activating enzyme E1 (>60% inhibition at 10 uM) with little or no activity against E2 or E3. Cell permeable. More details

$225 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Pyr41, Small Molecule
Full Product Name
Pyr41
Product Gene Name
Product Synonym Names
E1 UAE inhibitor; Ethyl 4-{(4Z)-4-[(5-nitro-2-furyl)methylene]-3,5-dioxo-1-pyrazolidinyl}benzoate; PYR-41; 4[4-(5-Nitro-furan-2-ylmethylene)-3,5-dioxo-pyrazolidin-1-yl]-benzoic acid ethyl ester
Host
Synthetic
Form/Format
Brown Powder
Purity/Purification
>98%
Preparation and Storage
Store at -20 degree C.
Molecular Weight
371.3
Solubility
Soluble in 25 mg/ml DMSO
CAS Number
418805-02-4
Molecular Formula
C17H13N3O7
SMILES
CCOC(=O)C1=CC=C(C=C1)N2C(=O)/C(=C\C3=CC=C(O3)[N+](=O)[O-])/C(=O)N2
InChI
1S/C17H13N3O7/c1-2-26-17(23)10-3-5-11(6-4-10)19-16(22)13(15(21)18-19)9-12-7-8-14(27-12)20(24)25/h3-9H,2H2,1H3,(H,18,21)/b13-9-
InChI Key
ARGIPZKQJGFSGQ-LCYFTJDESA-N
PubChem CID
5335621

Chemical Structure of Pyr41 small molecule

Chemical structure of Pyr41 (SIH-330), a E1 UAE inhibitor. CAS #: 418805-02-4. Molecular Formula: C17H13N3O7 . Molecular Weight: 371.3 g/mol.
PYR41 Small Molecule – Cat# MBS808035

Product References and Citations for Pyr41 small molecule

1. Yang Y., et al. (2007) Cancer Res. 67: 9472. 2. Mi L., et al. (2009) J. Biol. Chem. 284: 17039.

Other Notes

Small volumes of Pyr41 small molecule vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Pyr41 purchase

MBS808035 is a small molecule targeting Pyr41. Host: Synthetic.
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