Chemical structure of SB431542 (SIH-511), a ALK4,5 and 7 kinase inhibitor. CAS #: 301836-41-9. Molecular Formula: C22H16N4O3. Molecular Weight: 384.4 g/mol.

SB431542 Small Molecule

Name: SB431542 Small Molecule; MyBioSource
Brand: MyBioSource
SKU: MBS808210
Price: 305 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS808210

SB431542 is a potent and selective inhibitor of the transforming growth factor-beta (TGF-beta) type I receptor, activin receptor-like kinases. It has been shown to inhibit ALK4, 5, and 7. More details

$305 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SB431542, Small Molecule

Full Product Name

SB431542

Product Gene Name

SB431542 small molecule

Product Synonym Names

ALK4,5 and 7 kinase inhibitor; SB 431542; 4-(5-Benzol[1,3]dioxol-5-yl-4-pyrldin-2-yl-1H-imidazol-2-yl)-benzamide hydrate; 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-benzamide hydrate; 4-[4-(3,4-Methylenedioxyphenyl)-5-(2-pyridyl)-1H-imidazol-2-yl]-benzamide hydrate

Host

Synthetic

Form/Format

Yellow solid

Purity/Purification

>=98% (HPLC)

Preparation and Storage

Ships on blue ice. Store at 4°C.

Molecular Weight

384.4

Solubility

Soluble to 10 mM in ethanol and to 100 mM in DMSO

CAS Number

301836-41-9

Molecular Formula

C22H16N4O3

SMILES

C1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5

Research

Cell Signaling

Product Categories/Family for SB431542 small molecule

Small Molecules; Inhibitor; Cell Signaling; Cancer; Apoptosis; Cancer Growth Inhibitors; Tyrosine Kinase Inhibitors

Product References and Citations for SB431542 small molecule

1. Laping N.J., et al. (2002) Mol. Pharm. 62(1): 58-64.

Other Notes

Small volumes of SB431542 small molecule vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SB431542 purchase

MBS808210 is a small molecule targeting SB431542. Host: Synthetic.