Thymic Factor (TF) ELISA Kit for Monkey

Name: Monkey TF ELISA Kit; Thymic Factor; MyBioSource
Brand: MyBioSource
SKU: MBS075846
Price: 670 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS075846

MBS075846 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Thymic Factor (TF) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Product Name

Thymic Factor (TF), ELISA Kit

Full Product Name

Monkey Thymic Factor ELISA Kit

Product Gene Name

TF elisa kit

Species Reactivity

Monkey

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

35,003 Da

3D Structure

ModBase 3D Structure for O35235

Other Notes

Small volumes of TF elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TF. It may not necessarily be applicable to this product.

NCBI GI #

114842415

NCBI GeneID

21943

NCBI Accession #

NP_035743.2

UniProt Primary Accession #

O35235

UniProt Secondary Accession #

O35306; Q3TWY5; Q9JJK8; Q9JJK9; Q9R1Y0

UniProt Related Accession #

O35235

GenBank Nucleotide #

NM_011613.3

NCBI Official Full Name

tumor necrosis factor ligand superfamily member 11

NCBI Official Synonym Full Names

tumor necrosis factor (ligand) superfamily, member 11

NCBI Official Symbol

Tnfsf11

NCBI Official Synonym Symbols

ODF; OPG; OPGL; RANKL; Ly109l; Trance

UniProt Protein Name

Tumor necrosis factor ligand superfamily member 11

UniProt Synonym Protein Names

Osteoclast differentiation factor; ODF; Osteoprotegerin ligand; OPGL; Receptor activator of nuclear factor kappa-B ligand; RANKL; TNF-related activation-induced cytokine

Protein Family

Thymic factor

UniProt Gene Name

Tnfsf11

UniProt Synonym Gene Names

Opgl; Rankl; Trance; ODF; OPGL; RANKL; TRANCE

UniProt Entry Name

TNF11_MOUSE

NCBI Protein Information

tumor necrosis factor ligand superfamily member 11; OPG ligand; osteoprotegerin ligand; osteoclast differentiation factor; receptor activator of NF-kappaB ligand; TNF-related activation-induced cytokine; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; tumor necrosis factor-related activation-induced cytokine

UniProt Comments for TF

TNFSF11: Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy. Homotrimer. Up-regulated by T-cell receptor stimulation. Highest in the peripheral lymph nodes, weak in spleen, peripheral blood Leukocytes, bone marrow, heart, placenta, skeletal muscle, stomach and thyroid. Belongs to the tumor necrosis factor family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: extracellular space; membrane; cytoplasm; integral to membrane; plasma membrane; extracellular region; intracellular

Molecular Function: protein binding; cytokine activity; tumor necrosis factor receptor superfamily binding; tumor necrosis factor receptor binding

Biological Process: positive regulation of osteoclast differentiation; multicellular organismal development; positive regulation of JNK cascade; osteoclast differentiation; activation of JNK activity; activation of NF-kappaB transcription factor; positive regulation of corticotropin-releasing hormone secretion; positive regulation of homotypic cell-cell adhesion; calcium ion homeostasis; monocyte chemotaxis; positive regulation of MAP kinase activity; regulation of osteoclast differentiation; tumor necrosis factor-mediated signaling pathway; positive regulation of bone resorption; cell differentiation; protein homooligomerization; bone resorption; ossification; positive regulation of I-kappaB kinase/NF-kappaB cascade; cytokine and chemokine mediated signaling pathway; mammary gland epithelial cell proliferation; lymph node development; positive regulation of protein kinase B signaling cascade; organ morphogenesis; positive regulation of transcription factor activity; immune response; positive regulation of transcription from RNA polymerase II promoter; positive regulation of T cell activation; positive regulation of phosphorylation

Research Articles on TF

1. The OPG/RANKL/RANK axis plays critical roles in controlling inflammation in ischemic brains.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with TF elisa kit

Products by Pathway	Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
NF-kappa B Signaling Pathway antibodies	NF-kappa B Signaling Pathway Diagram
Osteoblast Pathway antibodies	Osteoblast Pathway Diagram
Osteoclast Pathway antibodies	Osteoclast Pathway Diagram
Osteoclast Differentiation Pathway antibodies	Osteoclast Differentiation Pathway Diagram
Osteoclast Differentiation Pathway antibodies	Osteoclast Differentiation Pathway Diagram
Prolactin Signaling Pathway antibodies	Prolactin Signaling Pathway Diagram
Prolactin Signaling Pathway antibodies	Prolactin Signaling Pathway Diagram
Rheumatoid Arthritis Pathway antibodies	Rheumatoid Arthritis Pathway Diagram

Diseases associated with TF elisa kit

Disease Name	Pubmed Publications
Necrosis Antibodies	>1520 publications with TF and Necrosis
Osteoporosis Antibodies	>1092 publications with TF and Osteoporosis
Neoplasms Antibodies	>918 publications with TF and Neoplasms
Inflammation Antibodies	>506 publications with TF and Inflammation
Osteolysis Antibodies	>342 publications with TF and Osteolysis
Cardiovascular Diseases Antibodies	>306 publications with TF and Cardiovascular Diseases
Breast Neoplasms Antibodies	>226 publications with TF and Breast Neoplasms
Alveolar Bone Loss Antibodies	>144 publications with TF and Alveolar Bone Loss
Pain Antibodies	>124 publications with TF and Pain
Osteopetrosis Antibodies	>121 publications with TF and Osteopetrosis

Organs/Tissues associated with TF elisa kit

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>4399 publications with TF and Bone
Spleen Antibodies	>146 publications with TF and Spleen
Thymus Antibodies	>39 publications with TF and Thymus