Rabbit Anti-FADS3 Polyclonal Antibody – Cat# MBS129659

Western blot analysis of extracts of various cell lines, using FADS3 antibody at 1:3000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.

FADS3 Antibody – Rabbit Polyclonal

Name: FADS3 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS129659
Price: 225 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS129659

The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members… More details

$225 / 0.02 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FADS3, Polyclonal Antibody

Full Product Name

FADS3 Polyclonal Antibody

Product Gene Name

anti-FADS3 antibody

Product Synonym Names

CYB5RP; LLCDL3

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Affinity Purification

Concentration

1mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

445

OMIM

606150

3D Structure

ModBase 3D Structure for Q9Y5Q0

Species

Human

Immunogen

Recombinant protein of human FADS3

Calculated Molecular Weight

51kDa

Product Categories/Family for anti-FADS3 antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-FADS3 antibody

Western Blot (WB)

Application Notes for anti-FADS3 antibody

WB: 1:500-1:2000

Other Notes

Small volumes of anti-FADS3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FADS3 purchase

MBS129659 is an antibody targeting FADS3. Also known as FADS3 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FADS3. It may not necessarily be applicable to this product.

NCBI GI #

74762790

NCBI GeneID

3995

NCBI Accession #

Q9Y5Q0.1

UniProt Primary Accession #

Q9Y5Q0

UniProt Secondary Accession #

O60426

UniProt Related Accession #

Q9Y5Q0

NCBI Official Full Name

Fatty acid desaturase 3

NCBI Official Synonym Full Names

fatty acid desaturase 3

NCBI Official Symbol

FADS3

NCBI Official Synonym Symbols

CYB5RP; LLCDL3

UniProt Protein Name

Fatty acid desaturase 3

UniProt Synonym Protein Names

Cytochrome b5-related protein

Protein Family

Fatty acid desaturase

UniProt Gene Name

FADS3

UniProt Synonym Gene Names

CYB5RP

UniProt Entry Name

FADS3_HUMAN

NCBI Protein Information

fatty acid desaturase 3; delta-9-desaturase; cytochrome b5-related protein; delta-9 fatty acid desaturase; linoleoyl-CoA desaturase (delta-9-desaturase)-like 3

UniProt Comments for FADS3

FADS3: is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. [provided by RefSeq, Jul 2008]

Protein type: Membrane protein, multi-pass; EC 1.14.19.-; Membrane protein, integral; Oxidoreductase

Chromosomal Location of Human Ortholog: 11q12-q13.1

Cellular Component: endoplasmic reticulum membrane; membrane; integral to membrane

Molecular Function: iron ion binding; heme binding; oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water

Biological Process: unsaturated fatty acid biosynthetic process

Research Articles on FADS3

1. Data suggest that FADS3 alternative transcripts/splicing are up-regulated in liver by dietary docosahexaenoic/arachidonic acids by peroxisome proliferator-activated receptor gamma (PPARg)-dependent mechanism unrelated to other desaturases (FADS1/2).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FADS3 antibody

Reference Product	PubMed Publications
ELOVL2 antibody	>2 publications with FADS3 and ELOVL2
SCD antibody	>1 publications with FADS3 and SCD

Diseases associated with anti-FADS3 antibody

Disease Name	Pubmed Publications
Fatty Liver Antibodies	>4 publications with FADS3 and Fatty Liver
Heart Diseases Antibodies	>3 publications with FADS3 and Heart Diseases
Nervous System Diseases Antibodies	>2 publications with FADS3 and Nervous System Diseases
Inflammation Antibodies	>2 publications with FADS3 and Inflammation
Hypertension Antibodies	>1 publications with FADS3 and Hypertension
Disease Models, Animal Antibodies	>1 publications with FADS3 and Disease Models, Animal

Organs/Tissues associated with anti-FADS3 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>12 publications with FADS3 and Blood
Liver Antibodies	>5 publications with FADS3 and Liver
Heart Antibodies	>3 publications with FADS3 and Heart
Brain Antibodies	>3 publications with FADS3 and Brain
Adipose Tissue Antibodies	>2 publications with FADS3 and Adipose Tissue
Spleen Antibodies	>1 publications with FADS3 and Spleen
Bone Marrow Antibodies	>1 publications with FADS3 and Bone Marrow
Uterus Antibodies	>1 publications with FADS3 and Uterus
Embryonic Tissue Antibodies	>1 publications with FADS3 and Embryonic Tissue
Lung Antibodies	>1 publications with FADS3 and Lung