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DNA Replication Licensing Factor MCM6 (MCM6) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1404294

This protein is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication… More details

$1310 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DNA replication licensing factor MCM6 (Mcm6), Recombinant Protein
Full Product Name
Recombinant Rat DNA replication licensing factor MCM6 (Mcm6)
Product Gene Name
Mcm6 recombinant protein
Product Synonym Gene Name
Mcm6
Sequence
LRDEEQTAES IKNQMTVKEW EKVFEMSQDQ NLYHNLCTSL FPTIHGNDEV KRGVLLMLFG GVPKTTGEGT SLRGDINVCI VGDPSTAKSQ FLKHVDEFSP RAVYTSGKAS SASGLTAAVV RDEESHEFVI EAGALMLADN GVCCIDEFDK MDMRDQVAIH EAMEQQTISI TKAGVKATLN ARTSILAAAN PVSGHYDRSK SLKQNINLSA PIMSRFDLFF ILVDECNEVT DYAIARRIVD LHSRIEESID RVYSLDDIRR YLLFARQFKP KISKESEDFI VEQYKRLRQR DGSGITKSSW RITVRQLESM IRLSESMARM HCCDEVQPKH VKEAFRLLNK SIIRVETPDV NLDQEEEIQM ETDEGPGGIN GHADSPAPVN GFNGSGEDAS QETVPKPSLR LAFAEYCRIS NLIVLHLRKM EEEEDESALK RSELVNWYLK EIESEIDSEE ELINKKRIIE KVVHRLTHYD HVLIELTQAG LKGSSEGSES YEEDPYLVVN PNYLLED
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
57,370 Da
Sequence Positions
1-507, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q62724
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Mcm6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Mcm6 purchase

MBS1404294 is a recombinant protein targeting Mcm6. Also known as Recombinant Rat DNA replication licensing factor MCM6 (Mcm6). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Mcm6. It may not necessarily be applicable to this product.

NCBI GI #
6016535
NCBI GeneID
29685
NCBI Accession #
Q62724.2
UniProt Primary Accession #
Q62724
UniProt Related Accession #
Q62724
NCBI Official Full Name
DNA replication licensing factor MCM6
NCBI Official Synonym Full Names
minichromosome maintenance complex component 6
NCBI Official Symbol
Mcm6
NCBI Official Synonym Symbols
Mcmd6
UniProt Protein Name
DNA replication licensing factor MCM6
UniProt Synonym Protein Names
Intestinal DNA replication protein
Protein Family
DNA replication licensing factor
UniProt Gene Name
Mcm6
UniProt Synonym Gene Names
Mcmd6
NCBI Protein Information
DNA replication licensing factor MCM6

NCBI Summary for Mcm6

belongs to a family of early S-phase proteins required for DNA replication; may play a role in cell-cycle progression and DNA replication [RGD, Feb 2006]

UniProt Comments for Mcm6

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Mcm6 recombinant protein

 Reference Product  PubMed Publications
 Mcm2 recombinant protein  >79 publications with Mcm6 and Mcm2
 Mcm4 recombinant protein  >68 publications with Mcm6 and Mcm4
 Mcm7 recombinant protein  >56 publications with Mcm6 and Mcm7
 Mcm3 recombinant protein  >36 publications with Mcm6 and Mcm3
 Mcm5 recombinant protein  >30 publications with Mcm6 and Mcm5
 Cdc7 recombinant protein  >9 publications with Mcm6 and Cdc7
 Orc1l recombinant protein  >1 publications with Mcm6 and Orc1l

Pathways associated with Mcm6 recombinant protein

 Products by Pathway  Pathway Diagram
 Activation Of ATR In Response To Replication Stress Pathway antibodies  Activation Of ATR In Response To Replication Stress Pathway Diagram
 Activation Of The Pre-replicative Complex Pathway antibodies  Activation Of The Pre-replicative Complex Pathway Diagram
 Assembly Of The Pre-replicative Complex Pathway antibodies  Assembly Of The Pre-replicative Complex Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 DNA Replication Pathway antibodies  DNA Replication Pathway Diagram

Organs/Tissues associated with Mcm6 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >9 publications with Mcm6 and Lung
 Liver Antibodies  >4 publications with Mcm6 and Liver
 Brain Antibodies  >4 publications with Mcm6 and Brain
 Ovary Antibodies  >3 publications with Mcm6 and Ovary
 Kidney Antibodies  >2 publications with Mcm6 and Kidney
 Small Intestine Antibodies  >2 publications with Mcm6 and Small Intestine
 Heart Antibodies  >2 publications with Mcm6 and Heart
 Placenta Antibodies  >1 publications with Mcm6 and Placenta
 Embryonic Tissue Antibodies  >1 publications with Mcm6 and Embryonic Tissue
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