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Glutamic-Oxaloacetic Transaminase 1 (GOT1) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140590

Introduction: GOT1 is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, which participate in amino acid metabolism and the urea and tricarboxylic acid cycles. Both enzymes are homodimeric and show close… More details

$250 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Glutamic-Oxaloacetic Transaminase 1 (GOT1), Recombinant Protein
Full Product Name
Recombinant Mouse Glutamic-Oxaloacetic Transaminase 1
Product Gene Name
GOT1 recombinant protein
Product Synonym Gene Name
mGOT1
Product Synonym Names
GOT1 Mouse; Glutamic-Oxaloacetic Transaminase 1 Mouse Recombinant; Aspartate aminotransferase; cytoplasmic; cAspAT; Cysteine aminotransferase; cytoplasmic; Cysteine transaminase; cytoplasmic; cCAT; Glutamate oxaloacetate transaminase 1; Transaminase A
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMAP PSVF AQVPQAPPVL VFKLTADFRD DPDPRKVNLG VGAYRTDESQ PWVLPVVRKV EQKIANDNSL NHEYLPILGL AEFRSCASRL VLGDNSPAIR ENRVGGVQSL GGTGALRIGA DFLGRWYNGT DNKNTPIYVS SPTWENHNAV FSAAGFKDIR PYCYWDAEKR GLDLQGFLND LENAPEFSIF VLHACAHNPT GTDPTPEQWK QIAAVMQRRF LFPFFDSAYQ GFASGDLEKD AWAIRYFVSE GFELFCAQSF SKNFGLYNER VGNLTVVGKE SDSVLRVLSQ MEKIVRITWS NPPAQGARIV AATLSDPELF KEWKGNVKTM ADRILTMRSE LRARLEALKT PGTWSHITEQ IGMFSFTGLN PKQVEYLVNE KHIYLLPSGR INMCGLTTKN LDYVATSIHE AVTKIQ
Host
E Coli
Form/Format
GOT1 protein solution (0.5mg/ml) containing Phosphate buffered saline (pH7.4), 10% glycerol and 1mM DTT.
Sterile filtered colorless solution.
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Molecular Weight
46,248 Da
3D Structure
ModBase 3D Structure for P05201

Product Categories/Family for GOT1 recombinant protein

Enzymes

Other Notes

Small volumes of GOT1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GOT1 purchase

MBS140590 is a recombinant protein targeting GOT1. Also known as Recombinant Mouse Glutamic-Oxaloacetic Transaminase 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GOT1. It may not necessarily be applicable to this product.

NCBI GI #
160298209
NCBI GeneID
14718
NCBI Accession #
NP_034454.2
UniProt Primary Accession #
P05201
UniProt Secondary Accession #
Q3UJH8
UniProt Related Accession #
P05201
GenBank Nucleotide #
NM_010324.2
NCBI Official Full Name
aspartate aminotransferase, cytoplasmic
NCBI Official Synonym Full Names
glutamic-oxaloacetic transaminase 1, soluble
NCBI Official Symbol
Got1
NCBI Official Synonym Symbols
cCAT; Got-1; cAspAT; AI789014
UniProt Protein Name
Aspartate aminotransferase, cytoplasmic
UniProt Synonym Protein Names
Cysteine aminotransferase, cytoplasmic; Cysteine transaminase, cytoplasmic; cCAT; Glutamate oxaloacetate transaminase 1; Transaminase A
Protein Family
Aspartate aminotransferase
UniProt Gene Name
Got1
UniProt Synonym Gene Names
cAspAT; cCAT
UniProt Entry Name
AATC_MOUSE
NCBI Protein Information
aspartate aminotransferase, cytoplasmic

UniProt Comments for GOT1

GOT1: Plays a key role in amino acid metabolism. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

Protein type: Amino Acid Metabolism - alanine, aspartate and glutamate; Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - cysteine and methionine; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - phenylalanine, tyrosine and tryptophan biosynthesis; Amino Acid Metabolism - tyrosine; EC 2.6.1.1; EC 2.6.1.3; Transferase

Cellular Component: cytoplasm; cytosol; lysosome; nerve terminal; nucleus

Molecular Function: aspartate transaminase activity; carboxylic acid binding; cysteine transaminase activity; identical protein binding; phosphatidylserine decarboxylase activity; pyridoxal phosphate binding

Biological Process: aspartate biosynthetic process; aspartate catabolic process; aspartate metabolic process; dicarboxylic acid metabolic process; fatty acid homeostasis; glutamate catabolic process to 2-oxoglutarate; glutamate catabolic process to aspartate; glycerol biosynthetic process; Notch signaling pathway; oxaloacetate metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with GOT1 recombinant protein

 Products by Pathway  Pathway Diagram
 2-Oxocarboxylic Acid Metabolism Pathway antibodies  2-Oxocarboxylic Acid Metabolism Pathway Diagram
 2-Oxocarboxylic Acid Metabolism Pathway antibodies  2-Oxocarboxylic Acid Metabolism Pathway Diagram
 4-hydroxyproline Degradation I Pathway antibodies  4-hydroxyproline Degradation I Pathway Diagram
 Alanine And Aspartate Metabolism Pathway antibodies  Alanine And Aspartate Metabolism Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Amino Acid Metabolism Pathway antibodies  Amino Acid Metabolism Pathway Diagram
 Amino Acid Synthesis And Interconversion (transamination) Pathway antibodies  Amino Acid Synthesis And Interconversion (transamination) Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram

Diseases associated with GOT1 recombinant protein

 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >6 publications with GOT1 and Lung Neoplasms
 Disease Models, Animal Antibodies  >5 publications with GOT1 and Disease Models, Animal
 Nervous System Diseases Antibodies  >5 publications with GOT1 and Nervous System Diseases
 Liver Diseases Antibodies  >4 publications with GOT1 and Liver Diseases
 Fatty Liver Antibodies  >3 publications with GOT1 and Fatty Liver
 Brain Diseases Antibodies  >3 publications with GOT1 and Brain Diseases
 Congenital Abnormalities Antibodies  >3 publications with GOT1 and Congenital Abnormalities
 Cardiovascular Diseases Antibodies  >3 publications with GOT1 and Cardiovascular Diseases
 Liver Neoplasms Antibodies  >2 publications with GOT1 and Liver Neoplasms
 Neoplasm Metastasis Antibodies  >2 publications with GOT1 and Neoplasm Metastasis

Organs/Tissues associated with GOT1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >17 publications with GOT1 and Blood
 Liver Antibodies  >8 publications with GOT1 and Liver
 Lung Antibodies  >7 publications with GOT1 and Lung
 Brain Antibodies  >5 publications with GOT1 and Brain
 Heart Antibodies  >4 publications with GOT1 and Heart
 Intestine Antibodies  >4 publications with GOT1 and Intestine
 Spinal Cord Antibodies  >3 publications with GOT1 and Spinal Cord
 Muscle Antibodies  >3 publications with GOT1 and Muscle
 Bone Antibodies  >2 publications with GOT1 and Bone
 Prostate Antibodies  >1 publications with GOT1 and Prostate
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