• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Syntaphilin (SNPH) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS143600

Description: SNPH Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 444 amino acids (1-424) and having a molecular mass of 48.2 kDa.The SNPH is fused to 20 amino acid His-Tag at N-terminus and purified by standard… More details

$250 / 0.01 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Syntaphilin (SNPH), Recombinant Protein
Full Product Name
Recombinant Human Syntaphilin
Product Gene Name
SNPH recombinant protein
Product Synonym Names
SNPH Human; Syntaphilin Human Recombinant; KIAA0374; MGC46096; bA314N13.5; SNPH; Syntaphilin
Sequence
MGSSHHH HHH SSGLVPRGSH MAMSLPGSRR TSAGSRRRTS PPVSVRDAYG TSSLSSSSNS GSYKGSDSSP TPRRSMKYTL CSDNHGIKPP TPEQYLTPLQ QKEVCIRHLK ARLKDTQDRL QDRDTEIDDL KTQLSRMQED WIEEECHRVE AQLALKEARK EIKQLKQVID TVKNNLIDKD KGLQKYFVDI NIQNKKLETL LHSMEVAQNG MAKEDGTGES AGGSPARSLT RSSTYTKLSD PAVCGDRQPG DPSSGSAEDG ADSGFAAADD TLSRTDALEA SSLLSSGVDC GTEETSLHSS FGLGPRFPAS NTYEKLLCGM EAGVQASCMQ ERAIQTDFVQ YQPDLDTILE KVTQAQVCGT DPESGDRCPE LDAHPSGPRD PNSAVVVTVG DELEAPEPIT RGPTPQRPGA NPNPGQSVSV VCPMEEEEEA AVAEKEPKSY WSRH
Host
E Coli
Form/Format
The Syntaphilin protein solution contains 20mM Tris-HCl pH-8, 1mM DTT and 10% glycerol.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Preparation and Storage
SNPH although stable 4 degree C for 4 weeks, should be stored desiccated below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Molecular Weight
57,990 Da
OMIM
604942
3D Structure
ModBase 3D Structure for O15079

Product Categories/Family for SNPH recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins

Other Notes

Small volumes of SNPH recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SNPH purchase

MBS143600 is a recombinant protein targeting SNPH. Also known as Recombinant Human Syntaphilin. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for SNPH. It may not necessarily be applicable to this product.

NCBI GI #
38202246
NCBI GeneID
9751
NCBI Accession #
NP_055538.2
UniProt Primary Accession #
O15079
UniProt Secondary Accession #
Q8IYI3
UniProt Related Accession #
O15079
GenBank Nucleotide #
NM_014723.2
NCBI Official Full Name
syntaphilin
NCBI Official Synonym Full Names
syntaphilin
NCBI Official Symbol
SNPH
NCBI Official Synonym Symbols
bA314N13.5
UniProt Protein Name
Syntaphilin
Protein Family
Syntaphilin
UniProt Gene Name
SNPH
UniProt Synonym Gene Names
KIAA0374
UniProt Entry Name
SNPH_HUMAN
NCBI Protein Information
syntaphilin

NCBI Summary for SNPH

Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for SNPH

syntaphilin: Inhibits SNARE complex formation by absorbing free syntaxin-1. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle; Membrane protein, integral

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: presynaptic membrane; neuron projection; cell soma; cytoplasmic microtubule; mitochondrial membrane; cytoplasm; integral to membrane; cell junction

Molecular Function: syntaxin-1 binding

Biological Process: neuron differentiation; neurotransmitter secretion; brain development; synaptic vesicle docking during exocytosis
Show more

Research Articles on SNPH

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SNPH recombinant protein

 Reference Product  PubMed Publications
 STX1A recombinant protein  >4 publications with SNPH and STX1A
 CPLX4 recombinant protein  >1 publications with SNPH and CPLX4
 SYP recombinant protein  >1 publications with SNPH and SYP
 DYNLL1 recombinant protein  >1 publications with SNPH and DYNLL1

Diseases associated with SNPH recombinant protein

 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >7 publications with SNPH and Brain Diseases
 Cardiovascular Diseases Antibodies  >2 publications with SNPH and Cardiovascular Diseases
 Hemorrhage Antibodies  >2 publications with SNPH and Hemorrhage
 Weight Loss Antibodies  >1 publications with SNPH and Weight Loss
 Abdominal Pain Antibodies  >1 publications with SNPH and Abdominal Pain
 Coma Antibodies  >1 publications with SNPH and Coma

Organs/Tissues associated with SNPH recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >10 publications with SNPH and Brain
 Lung Antibodies  >2 publications with SNPH and Lung
 Liver Antibodies  >2 publications with SNPH and Liver
 Kidney Antibodies  >2 publications with SNPH and Kidney
 Intestine Antibodies  >1 publications with SNPH and Intestine
 Eye Antibodies  >1 publications with SNPH and Eye
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000