Human Bone BMP 5 Recombinant Protein – Cat# MBS143774

Morphogenetic Protein-5 (BMP 5) Human Bone Recombinant Protein

Name: BMP 5 Recombinant Protein; Morphogenetic Protein-5; Human Bone; MyBioSource
Brand: MyBioSource
SKU: MBS143774
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS143774

Description: BMP-5 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 139 amino acids (317-454 a.a.) and having a total molecular mass of 15.7 kDa.BMP-5 is purified by proprietary chromatographic… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Morphogenetic protein-5 (BMP 5), Recombinant Protein

Full Product Name

Recombinant Human Bone Morphogenetic protein-5

Product Gene Name

BMP 5 recombinant protein

Product Synonym Names

BMP 5 Human; Bone Morphogenetic protein-5 Human Recombinant; Bone morphogenetic protein 5; BMP-5; BMP5; MGC34244

Sequence

MAANKRKNQN RNKSSSHQDS SRMSSVGDYN TSEQKQACKK HELYVSFRDL GWQDWIIAPE GYAAFYCDGE CSFPLNAHMN ATNHAIVQTL VHLMFPDHVP KPCCAPTKLN AISVLYFDDS SNVILKKYRN MVVRSCGCH

Host

E Coli

Form/Format

The BMP-5 solution contains 10mM Sodium Citrate buffer (pH3.5) and 10% Glycerol.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 95.0% as determined by SDS-PAGE.

Molecular Weight

47,670 Da

OMIM

112265

3D Structure

ModBase 3D Structure for P22003

Product Categories/Family for BMP 5 recombinant protein

Cytokines and Growth Factors; Cytokines; Bone Morphogenetic Protein

Other Notes

Small volumes of BMP 5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BMP 5 purchase

MBS143774 is a recombinant protein targeting BMP 5. Also known as Recombinant Human Bone Morphogenetic protein-5. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for BMP 5. It may not necessarily be applicable to this product.

NCBI GI #

10835091

NCBI GeneID

653

NCBI Accession #

NP_066551.1

UniProt Primary Accession #

P22003

UniProt Secondary Accession #

Q9H547; Q9NTM5; B4E0Y4

UniProt Related Accession #

P22003

GenBank Nucleotide #

NM_021073.2

NCBI Official Full Name

bone morphogenetic protein 5 preproprotein

NCBI Official Synonym Full Names

bone morphogenetic protein 5

NCBI Official Symbol

BMP5

UniProt Protein Name

Bone morphogenetic protein 5

Protein Family

Bone morphogenetic protein

UniProt Gene Name

BMP5

UniProt Synonym Gene Names

BMP-5

UniProt Entry Name

BMP5_HUMAN

NCBI Protein Information

bone morphogenetic protein 5; BMP-5; bone morphogenenic protein-5

NCBI Summary for BMP 5

This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors. [provided by RefSeq, Jul 2008]

UniProt Comments for BMP 5

BMP5: Induces cartilage and bone formation. Belongs to the TGF-beta family.

Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 6p12.1

Cellular Component: extracellular space

Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: ossification; negative regulation of insulin-like growth factor receptor signaling pathway; pattern specification process; BMP signaling pathway; regulation of apoptosis; negative regulation of cell proliferation; cartilage development; regulation of MAPKKK cascade; negative regulation of aldosterone biosynthetic process; male genitalia development; positive regulation of transcription from RNA polymerase II promoter; skeletal development; positive regulation of epithelial cell proliferation; growth

Research Articles on BMP 5

1. BMP5, is elevated in the stenotic colon segment of Hirschsprung disease patients, and BMP5 signaling may play a pivotal role in disease development.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with BMP 5 recombinant protein

Reference Product	PubMed Publications
BMPR1A recombinant protein	>4 publications with BMP 5 and BMPR1A
BMPR2 recombinant protein	>3 publications with BMP 5 and BMPR2
FST recombinant protein	>2 publications with BMP 5 and FST
AMHR2 recombinant protein	>1 publications with BMP 5 and AMHR2
SOST recombinant protein	>1 publications with BMP 5 and SOST

Pathways associated with BMP 5 recombinant protein

Products by Pathway	Pathway Diagram
BMP Signaling Pathway antibodies	BMP Signaling Pathway Diagram
BMP Signaling Pathway antibodies	BMP Signaling Pathway Diagram
Hippo Signaling Pathway antibodies	Hippo Signaling Pathway Diagram
Hippo Signaling Pathway antibodies	Hippo Signaling Pathway Diagram
TGF-beta Signaling Pathway antibodies	TGF-beta Signaling Pathway Diagram
TGF-beta Signaling Pathway antibodies	TGF-beta Signaling Pathway Diagram

Diseases associated with BMP 5 recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>6 publications with BMP 5 and Inflammation
Fibrosis Antibodies	>4 publications with BMP 5 and Fibrosis
Carcinoma Antibodies	>4 publications with BMP 5 and Carcinoma
Nervous System Diseases Antibodies	>4 publications with BMP 5 and Nervous System Diseases
Necrosis Antibodies	>3 publications with BMP 5 and Necrosis
Breast Neoplasms Antibodies	>2 publications with BMP 5 and Breast Neoplasms
Cell Transformation, Neoplastic Antibodies	>2 publications with BMP 5 and Cell Transformation, Neoplastic
Hypertrophy Antibodies	>2 publications with BMP 5 and Hypertrophy
Kidney Diseases Antibodies	>2 publications with BMP 5 and Kidney Diseases
Proteinuria Antibodies	>2 publications with BMP 5 and Proteinuria

Organs/Tissues associated with BMP 5 recombinant protein

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>23 publications with BMP 5 and Embryonic Tissue
Connective Tissue Antibodies	>17 publications with BMP 5 and Connective Tissue
Muscle Antibodies	>14 publications with BMP 5 and Muscle
Brain Antibodies	>9 publications with BMP 5 and Brain
Heart Antibodies	>8 publications with BMP 5 and Heart
Eye Antibodies	>5 publications with BMP 5 and Eye
Prostate Antibodies	>5 publications with BMP 5 and Prostate
Lung Antibodies	>4 publications with BMP 5 and Lung
Liver Antibodies	>4 publications with BMP 5 and Liver
Pancreas Antibodies	>3 publications with BMP 5 and Pancreas