Mouse mIFNB Recombinant Protein – Cat# MBS143787

Interferon-Beta (mIFNB) Mouse Recombinant Protein

Name: mIFNB Recombinant Protein; Interferon-Beta; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS143787
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS143787

Description: Interferon beta Mouse Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 182 amino acids (22-182 a.a.) and having a molecular mass of 22 kDa. Mouse IFN beta is fused to 20 amino acid at N-terminus and… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Interferon-beta (mIFNB), Recombinant Protein

Full Product Name

Recombinant Mouse Interferon-beta

Product Gene Name

mIFNB recombinant protein

Product Synonym Names

IFN b Mouse, His; Interferon Beta Mouse Recombinant, His Tag; Leukocyte interferon; B cell interferon; Type I interferon; IFNB1; IFB; IFF; IFNB; IFN-b 1b; MGC96956

Sequence

MGSSHHHHHH SSGLVPRGSH MINYKQLQLQ ERTNIRKCQE LLEQLNGKIN LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN

Host

E Coli

Form/Format

The IFN-Beta (0.25mg/ml) contains 20mM HEPES (pH6.0), 0.5M NaCl & 10% glycerol.
Sterile filtered colorless solution.

Purity/Purification

Greater than 95% as determined by Analysis by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

Molecular Weight

22,127 Da

3D Structure

ModBase 3D Structure for P01575

Product Categories/Family for mIFNB recombinant protein

Cytokines and Growth Factors; Cytokines; Interferon

Other Notes

Small volumes of mIFNB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for mIFNB purchase

MBS143787 is a recombinant protein targeting mIFNB. Also known as Recombinant Mouse Interferon-beta. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for mIFNB. It may not necessarily be applicable to this product.

NCBI GI #

6754304

NCBI GeneID

15977

NCBI Accession #

NP_034640.1

UniProt Primary Accession #

P01575

UniProt Related Accession #

P01575

GenBank Nucleotide #

NM_010510.1

NCBI Official Full Name

interferon beta

NCBI Official Synonym Full Names

interferon beta 1, fibroblast

NCBI Official Symbol

Ifnb1

NCBI Official Synonym Symbols

Ifb; IFNB; IFN-beta

UniProt Protein Name

Interferon beta

Protein Family

Interferon

UniProt Gene Name

Ifnb1

UniProt Synonym Gene Names

Ifb; Ifnb; IFN-beta

UniProt Entry Name

IFNB_MOUSE

NCBI Protein Information

interferon beta

UniProt Comments for mIFNB

IFNB1: Has antiviral, antibacterial and anticancer activities. Belongs to the alpha/beta interferon family.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; extracellular region

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor binding; interferon-alpha/beta receptor binding; cytokine activity

Biological Process: B cell proliferation; adaptive immune response; cytokine and chemokine mediated signaling pathway; regulation of MHC class I biosynthetic process; defense response; negative regulation of T cell differentiation; humoral immune response; T cell activation during immune response; response to exogenous dsRNA; negative regulation of viral genome replication; B cell differentiation; defense response to bacterium; natural killer cell activation during immune response; innate immune response; positive regulation of transcription from RNA polymerase II promoter; defense response to virus; B cell activation during immune response; positive regulation of peptidyl-serine phosphorylation of STAT protein

Research Articles on mIFNB

1. These results indicate that high Sendai virus replication in the lungs of infected Ifit2(-/-) mice cooperates with elevated IFN-beta induction to cause disease.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with mIFNB recombinant protein

Reference Product	PubMed Publications
Irf3 recombinant protein	>18 publications with mIFNB and Irf3
Ifnar1 recombinant protein	>6 publications with mIFNB and Ifnar1
Stat1 recombinant protein	>5 publications with mIFNB and Stat1
Stat2 recombinant protein	>3 publications with mIFNB and Stat2
Irf1 recombinant protein	>1 publications with mIFNB and Irf1
Ifnar2 recombinant protein	>1 publications with mIFNB and Ifnar2
Crebbp recombinant protein	>1 publications with mIFNB and Crebbp

Pathways associated with mIFNB recombinant protein

Products by Pathway	Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokines And Inflammatory Response (BioCarta) Pathway antibodies	Cytokines And Inflammatory Response (BioCarta) Pathway Diagram
Cytosolic DNA-sensing Pathway antibodies	Cytosolic DNA-sensing Pathway Diagram
Cytosolic DNA-sensing Pathway antibodies	Cytosolic DNA-sensing Pathway Diagram
EBV LMP1 Signaling Pathway antibodies	EBV LMP1 Signaling Pathway Diagram
Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies	Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram

Diseases associated with mIFNB recombinant protein

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>9 publications with mIFNB and Immune System Diseases
Inflammation Antibodies	>8 publications with mIFNB and Inflammation
Necrosis Antibodies	>7 publications with mIFNB and Necrosis
Carcinoma Antibodies	>4 publications with mIFNB and Carcinoma
Melanoma Antibodies	>3 publications with mIFNB and Melanoma
Leukemia Antibodies	>3 publications with mIFNB and Leukemia
Lung Neoplasms Antibodies	>3 publications with mIFNB and Lung Neoplasms
Heart Diseases Antibodies	>2 publications with mIFNB and Heart Diseases
Multiple Sclerosis Antibodies	>2 publications with mIFNB and Multiple Sclerosis
Pancreatic Neoplasms Antibodies	>2 publications with mIFNB and Pancreatic Neoplasms