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CD41/CD61 Antibody – Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1800811

CD41 (platelet glycoprotein IIb, integrin alpha IIb) is composed of two subunits (120 kDa transmembrane alpha chain and 23 kDa extracellular beta chain) and interacts with CD61 (platelet glycoprotein IIIa, integrin beta 3) in the presence of calcium to form a… More details

$295 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD41/CD61, Antibody
Full Product Name
Anti-Bov CD41/CD61 Purified
Product Gene Name
anti-CD41/CD61 antibody
Product Synonym Names
platelet GPIIb; Integrin alpha-IIb; GPalpha IIb; GPIIb; GT; GP3A; platelet GPIIIa
Isotype
IgG2
Clone Number
IVA30
Host
Mouse
Species Reactivity
Cow, Human
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Purity/Purification
Purified by Protein-A Affinity Chromatography
Concentration
1 mg/ml (lot specific)
Specificity
The antibody IVA30 reacts with an extracellular epitope on CD41/CD61 complex (bovine), one of the earliest markers of the megakaryocytic lineage. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor, vitronectin, thrombin and mediates platelets aggregation. CD41/CD61 is expressed only by platelets and megakaryocytes; the complex may be absent or strongly reduced in Glanzmann's thrombasthenia (GT). This antibody crossreacts with human platelets.
Preparation and Storage
Store at 2-8 degree C.
Immunogen
Bovine trombocytes.
Applications Tested/Suitable for anti-CD41/CD61 antibody
Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), ELISA (EIA)

Immunocytochemistry (ICC) of anti-CD41/CD61 antibody

Immunocytochemistry staining of acetone/methanol fixed bovine peripheral blood (thrombocyte-enriched suspension) using anti-bovine CD41/CD61 (IVA30); secondary antibody conjugated to FITC (green signal at thrombocytes), DNA stained with DAPI (blue signal).
Mouse Anti-CD41/CD61 Antibody – Cat# MBS1800811

Flow Cytometry (FC/FACS) of anti-CD41/CD61 antibody

Separation of human CD41/CD61 positive blood debris (red-filled) from CD41/CD61 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of peripheral whole blood stained using anti-bovine CD41/CD61 (IVA30) purified antibody (concentration in sample 0,3 ug/ml, GAM APC).
Mouse Anti-CD41/CD61 Antibody, Flow Cytometry (FC/FACS) – Cat# MBS1800811

Flow Cytometry (FC/FACS) of anti-CD41/CD61 antibody

Separation of bovine CD41/CD61 positive thrombocytes (red-filled) from CD41/CD61 negative leukocytes (black-dashed) in flow cytometry analysis (surface staining) of bovine peripheral whole blood stained using anti-bovine CD41/CD61 (IVA30) purified antibody (concentration in sample 3 ug/ml, GAM APC).
Mouse Anti-CD41/CD61 Antibody, Flow Cytometry (FC/FACS) – Cat# MBS1800811

Flow Cytometry (FC/FACS) of anti-CD41/CD61 antibody

Flow cytometry surface staining pattern of human peripheral whole blood using anti-bovine CD41/CD61 (IVA30) purified antibody (concentration in sample 0,3 ug/ml, GAM APC).
Mouse Anti-CD41/CD61 Antibody, Flow Cytometry (FC/FACS) – Cat# MBS1800811

Flow Cytometry (FC/FACS) of anti-CD41/CD61 antibody

Flow cytometry surface staining pattern of bovine peripheral whole blood stained using anti-bovine CD41/CD61 (IVA30) purified antibody (concentration in sample 3 ug/ml, GAM APC).
Mouse Anti-CD41/CD61 Antibody, Flow Cytometry (FC/FACS) – Cat# MBS1800811

Other Notes

Small volumes of anti-CD41/CD61 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD41/CD61 purchase

MBS1800811 is an antibody targeting CD41/CD61. Also known as Anti-Bov CD41/CD61 Purified. Reactive in Cow, Human. Host: Mouse.
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