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C4.4A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243479

C4.4A is a structural homolog of the urokinase-type plasminogen activator receptor (uPAR). It was originally identified as a metastasis-associated membrane protein in malignant urothelium. In literature IHC studies, staining has been observed in suprabasal… More details

$650 / 0.05 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
C4.4A / LYPD3, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human C4.4A / LYPD3
Product Gene Name
Product Synonym Gene Name
LYPD3
Product Synonym Names
Anti-C4.4A / LYPD3 Antibody (Internal) IHC-plus; LYPD3; C4.4A; MIG-C4; LY6/PLAUR domain containing 3; Human C4.4A; LYPD3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Gorilla, Human
Predicted Reactivity: Rabbit (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
0.7 mg/ml (lot specific)
Specificity
Human LYPD3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
Molecular Weight
35,971 Da
OMIM
609484
3D Structure
ModBase 3D Structure for O95274
Target Species
Human
Immunogen Description
Synthetic 14 amino acid peptide from internal region of human LYPD3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Rabbit (93%); Marmoset, Dog, Panda, Horse (86%).
Immunogen Type
Synthetic peptide
Immunogen
C4.4A / LYPD3 antibody was raised against synthetic 14 amino acid peptide from internal region of human LYPD3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Rabbit (93%); Marmoset, Dog, Panda, Horse (86%).
Antigen Modification
Internal
Applications Tested/Suitable for anti-C4.4A antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-C4.4A antibody
IHC-P (10 - 12.5 ug/ml)

Immunohistochemistry (IHC) of anti-C4.4A antibody

Anti-LYPD3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-C4.4A Polyclonal Antibody – Cat# MBS243479

Immunohistochemistry (IHC) of anti-C4.4A antibody

Anti-LYPD3 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-C4.4A Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS243479

Other Notes

Small volumes of anti-C4.4A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for C4.4A purchase

MBS243479 is an antibody targeting C4.4A. Also known as Rabbit Polyclonal to Human C4.4A / LYPD3. Reactive in Gibbon, Gorilla, Human
Predicted Reactivity: Rabbit (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for C4.4A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ly6/PLAUR domain-containing protein 3
NCBI Official Synonym Full Names
LY6/PLAUR domain containing 3
NCBI Official Symbol
LYPD3
NCBI Official Synonym Symbols
C4.4A
UniProt Protein Name
Ly6/PLAUR domain-containing protein 3
UniProt Synonym Protein Names
GPI-anchored metastasis-associated protein C4.4A homolog; Matrigel-induced gene C4 protein; MIG-C4
UniProt Gene Name
LYPD3
UniProt Synonym Gene Names
C4.4A; MIG-C4
UniProt Entry Name
LYPD3_HUMAN
NCBI Protein Information
ly6/PLAUR domain-containing protein 3; MIG-C4; 2310061G07Rik; matrigel-induced gene C4 protein; GPI-anchored metastasis-associated protein homolog; GPI-anchored metastasis-associated protein C4.4A homolog

UniProt Comments for C4.4A

LYPD3: Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression.

Protein type: Cell adhesion; Motility/polarity/chemotaxis; Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 19q13.31

Cellular Component: extracellular space; anchored to plasma membrane; integral to membrane

Molecular Function: laminin binding

Biological Process: cell-matrix adhesion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-C4.4A antibody

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