Amphiregulin (AREG) ELISA Kit for Horse

Name: Horse AREG ELISA Kit; Amphiregulin; MyBioSource
Brand: MyBioSource
SKU: MBS031604
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS031604

Background: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used to determine the level of AREG (hereafter termed "analyte") in undiluted original… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Amphiregulin (AREG), ELISA Kit

Full Product Name

Horse Amphiregulin ELISA Kit

Product Gene Name

AREG elisa kit

Species Reactivity

Horse

Assay Type

Quantitative Sandwich

Detection Range

31.2pg/ml-1000pg/ml

Sensitivity

5.0pg/ml

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

27,895 Da

Chromosome Location

Chromosome: 4; NC_000004.11 (75310853..75320726). Location: 4q13.3

OMIM

104640

3D Structure

ModBase 3D Structure for P15514

Other Notes

Small volumes of AREG elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AREG purchase

MBS031604 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Amphiregulin (AREG) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing AREG. The ELISA analytical biochemical technique of the MBS031604 kit is based on AREG antibody-AREG antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AREG antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AREG. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for AREG. It may not necessarily be applicable to this product.

NCBI GI #

4502199

NCBI GeneID

374

NCBI Accession #

NP_001648.1

UniProt Primary Accession #

P15514

UniProt Related Accession #

P15514

GenBank Nucleotide #

NM_001657.2

NCBI Official Full Name

amphiregulin preproprotein

NCBI Official Synonym Full Names

amphiregulin

NCBI Official Symbol

AREG

NCBI Official Synonym Symbols

AR; SDGF; CRDGF

UniProt Protein Name

Amphiregulin

UniProt Synonym Protein Names

Colorectum cell-derived growth factor

Protein Family

Amphiregulin

UniProt Gene Name

AREG

UniProt Synonym Gene Names

SDGF; AR; CRDGF

UniProt Entry Name

AREG_HUMAN

NCBI Protein Information

amphiregulin; schwannoma-derived growth factor; colorectum cell-derived growth factor

NCBI Summary for AREG

The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype. [provided by RefSeq, Jul 2008]

UniProt Comments for AREG

AREG: Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts. Belongs to the amphiregulin family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: extracellular space; cell surface; cytoplasm; integral to membrane; nucleus

Molecular Function: protein binding; growth factor activity; cytokine activity; epidermal growth factor receptor binding

Biological Process: epidermal growth factor receptor signaling pathway; response to peptide hormone stimulus; response to cAMP; response to glucocorticoid stimulus; response to estradiol stimulus; glial cell proliferation; cell proliferation; G-protein coupled receptor protein signaling pathway; response to hydrogen peroxide; cell-cell signaling; positive regulation of cell proliferation; negative regulation of osteoblast differentiation; positive regulation of DNA replication; neurite development; positive regulation of phosphorylation

Research Articles on AREG

1. Regulation of amphiregulin gene expression by beta-catenin signaling in human hepatocellular carcinoma cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with AREG elisa kit

Reference Product	PubMed Publications
EGFR elisa kit	>83 publications with AREG and EGFR
PTGS2 elisa kit	>30 publications with AREG and PTGS2
ERBB2 elisa kit	>12 publications with AREG and ERBB2
PGR elisa kit	>11 publications with AREG and PGR
ERBB3 elisa kit	>5 publications with AREG and ERBB3
ATF3 elisa kit	>2 publications with AREG and ATF3
PTHLH elisa kit	>1 publications with AREG and PTHLH
AKT1 elisa kit	>1 publications with AREG and AKT1

Pathways associated with AREG elisa kit

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Hippo Signaling Pathway antibodies	Hippo Signaling Pathway Diagram

Diseases associated with AREG elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>76 publications with AREG and Neoplasms
Carcinoma Antibodies	>32 publications with AREG and Carcinoma
Breast Neoplasms Antibodies	>26 publications with AREG and Breast Neoplasms
Inflammation Antibodies	>16 publications with AREG and Inflammation
Necrosis Antibodies	>16 publications with AREG and Necrosis
Adenocarcinoma Antibodies	>11 publications with AREG and Adenocarcinoma
Neoplasms, Experimental Antibodies	>11 publications with AREG and Neoplasms, Experimental
Neoplasm Metastasis Antibodies	>8 publications with AREG and Neoplasm Metastasis
Liver Diseases Antibodies	>8 publications with AREG and Liver Diseases
Cell Transformation, Neoplastic Antibodies	>8 publications with AREG and Cell Transformation, Neoplastic

Organs/Tissues associated with AREG elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>23 publications with AREG and Blood
Lung Antibodies	>18 publications with AREG and Lung
Mammary Gland Antibodies	>17 publications with AREG and Mammary Gland
Liver Antibodies	>12 publications with AREG and Liver
Skin Antibodies	>11 publications with AREG and Skin
Vascular Antibodies	>7 publications with AREG and Vascular
Prostate Antibodies	>7 publications with AREG and Prostate
Bone Marrow Antibodies	>6 publications with AREG and Bone Marrow
Intestine Antibodies	>5 publications with AREG and Intestine
Placenta Antibodies	>4 publications with AREG and Placenta