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INPP5J Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3206069

This is a rabbit polyclonal antibody against INPP5J. It was validated on Western Blot More details

$490 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
INPP5J, Polyclonal Antibody
Full Product Name
INPP5J Antibody - C-terminal region
Product Gene Name
anti-INPP5J antibody
Product Synonym Gene Name
PIPP; INPP5; PIB5PA
Immunogen Sequence
Synthetic peptide located within the following region: SSELASSSTD SSGTSSEGED DSTLELLAPK SRSPSPGKSK RHRSRSPGLA
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
INPP5J peptide (MBS3231032) is used for blocking the activity of INPP5J antibody (MBS3206069)
Molecular Weight
40kDa
OMIM
606481
3D Structure
ModBase 3D Structure for Q15735
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of human INPP5J

Product Categories/Family for anti-INPP5J antibody

Polyclonal; Neuroscience; Various
Applications Tested/Suitable for anti-INPP5J antibody
Western Blot (WB)

Western Blot (WB) of anti-INPP5J antibody

Host: Rabbit
Target Name: INPP5J
Sample Type: Jurkat Whole Cell lysates
Antibody Dilution: 1.0ug/ml
Rabbit Anti-INPP5J Polyclonal Antibody – Cat# MBS3206069

Other Notes

Small volumes of anti-INPP5J antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for INPP5J purchase

MBS3206069 is an antibody targeting INPP5J. Also known as INPP5J Antibody - C-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for INPP5J. It may not necessarily be applicable to this product.

NCBI GI #
50726960
NCBI GeneID
27124
NCBI Accession #
NP_001002837.1
UniProt Primary Accession #
Q15735
UniProt Related Accession #
Q15735
GenBank Nucleotide #
NM_001002837.2
NCBI Official Full Name
phosphatidylinositol 4,5-bisphosphate 5-phosphatase A isoform c
NCBI Official Synonym Full Names
inositol polyphosphate-5-phosphatase J
NCBI Official Symbol
INPP5J
NCBI Official Synonym Symbols
PIPP; INPP5; PIB5PA
UniProt Protein Name
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A
UniProt Synonym Protein Names
Inositol polyphosphate 5-phosphatase J
Protein Family
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase
UniProt Gene Name
INPP5J
UniProt Synonym Gene Names
PIB5PA; PIPP
UniProt Entry Name
PI5PA_HUMAN
NCBI Protein Information
phosphatidylinositol 4,5-bisphosphate 5-phosphatase A

UniProt Comments for INPP5J

PI5PA: Inositol 5-phosphatase, which converts inositol 1,4,5- trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4- phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate- binding proteins that are present at membranes ruffles. Belongs to the inositol 1,4,5-trisphosphate 5- phosphatase type II family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.56; Phosphatase (non-protein); Carbohydrate Metabolism - inositol phosphate

Chromosomal Location of Human Ortholog: 22q12.2

Cellular Component: ruffle; growth cone; cytoplasm; plasma membrane; dendritic shaft; cytosol

Molecular Function: inositol-polyphosphate 5-phosphatase activity; SH3 domain binding

Biological Process: inositol phosphate metabolic process; phospholipid metabolic process; negative regulation of microtubule polymerization; phosphatidylinositol biosynthetic process; negative regulation of peptidyl-serine phosphorylation; phosphoinositide dephosphorylation
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Research Articles on INPP5J

1. Suggest miR-661 functions as a tumor promoter by targeting the INPP5J gene, and then promoting cell proliferation of ovarian cancer cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-INPP5J antibody

 Reference Product  PubMed Publications
 PTEN antibody  >1 publications with INPP5J and PTEN
 INPP4A antibody  >1 publications with INPP5J and INPP4A

Pathways associated with anti-INPP5J antibody

 Products by Pathway  Pathway Diagram
 1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway antibodies  1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway Diagram
 1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway antibodies  1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway Diagram
 3-phosphoinositide Degradation Pathway antibodies  3-phosphoinositide Degradation Pathway Diagram
 3-phosphoinositide Degradation Pathway antibodies  3-phosphoinositide Degradation Pathway Diagram
 D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway antibodies  D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway Diagram
 D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway antibodies  D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway Diagram
 D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway antibodies  D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway Diagram
 D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway antibodies  D-myo-inositol (1,4,5)-trisphosphate Degradation Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram

Organs/Tissues associated with anti-INPP5J antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with INPP5J and Brain
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