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ASPH Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3210328

This is a rabbit polyclonal antibody against ASPH. It was validated on Western Blot and immunohistochemistryTarget Description: ASPH is thought to play an important role in calcium homeostasis. Alternative splicing of this gene results in five transcript… More details

$440 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
ASPH, Polyclonal Antibody
Full Product Name
ASPH antibody - N-terminal region
Product Gene Name
anti-ASPH antibody
Product Synonym Gene Name
BAH; CASQ2BP1; HAAH; JCTN; junctin; AAH
Immunogen Sequence
Synthetic peptide located within the following region: SEVLQGKLGI YDADGDGDFD VDDAKVLLEG PSGVAKRKTK AKVKELTKEE
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Protein A purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
ASPH peptide (MBS3235284) is used for blocking the activity of ASPH antibody (MBS3210328)
Molecular Weight
25kDa
3D Structure
ModBase 3D Structure for Q9NRI0
Homology
Dog: 93%; Horse: 83%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 86%; Rat: 86%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human ASPH

Product Categories/Family for anti-ASPH antibody

Polyclonal; Transcription Factor; Membrane Protein; Immunohistochemistry
Applications Tested/Suitable for anti-ASPH antibody
Immunohistochemistry (IHC), Western Blot (WB)

Immunohistochemistry (IHC) of anti-ASPH antibody

Human kidney
Rabbit Anti-ASPH Polyclonal Antibody – Cat# MBS3210328

Western Blot (WB) of anti-ASPH antibody

WB Suggested Anti-ASPH Antibody Titration: 2.5ug/ml
Positive Control: HepG2 cell lysateThere is BioGPS gene expression data showing that ASPH is expressed in HepG2
Rabbit Anti-ASPH Polyclonal Antibody, Western Blot (WB) – Cat# MBS3210328

Other Notes

Small volumes of anti-ASPH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ASPH purchase

MBS3210328 is an antibody targeting ASPH. Also known as ASPH antibody - N-terminal region. Reactive in Dog, Horse, Human, Mouse, Pig, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ASPH. It may not necessarily be applicable to this product.

NCBI GI #
9910364
NCBI GeneID
444
NCBI Accession #
NP_064549
UniProt Primary Accession #
Q9NRI0
UniProt Related Accession #
Q12797
GenBank Nucleotide #
NM_020164
NCBI Official Full Name
aspartyl/asparaginyl beta-hydroxylase isoform e
NCBI Official Synonym Full Names
aspartate beta-hydroxylase
NCBI Official Symbol
ASPH
NCBI Official Synonym Symbols
AAH; BAH; HAAH; JCTN; FDLAB; junctin; CASQ2BP1
Protein Family
Aspartyl/asparaginyl beta-hydroxylase
NCBI Protein Information
aspartyl/asparaginyl beta-hydroxylase

NCBI Summary for ASPH

This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis. [provided by RefSeq, Sep 2009]
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Research Articles on ASPH

1. The mRNA expression and promoter methylation rate of ASPH gene may play a role in the development and progression of breast cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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