Tesirine (SG3249)

Name: Tesirine (SG3249); MyBioSource
Brand: MyBioSource
SKU: MBS3602277
Price: 1590 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602277

Tesirine ( SG3249) is a cathepsin B-cleavable valine-alanine pyrrolobenzodiazepine (PBD) dimer as antibody-drug conjugate (ADC) payload. More details

$1590 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Tesirine, Biochemical

Full Product Name

Tesirine

Product Synonym Names

SG3249; SG-3249

Purity/Purification

Analytical data HPLC: 98% purity

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Target

Drug-Linker Conjugates

Receptor

Drug-Linker Conjugates

Chemical Name

4-((S)-N-((S)-1-amino-1-oxopropan-2-yl)-34-(2, 5-dioxo-2, 5-dihydro-1H-pyrrol-1-yl)-2-isopropyl-4, 32-dioxo-7, 10, 13, 16, 19, 22, 25, 28-octaoxa-3, 31-diazatetratriacontanamido)benzyl(11S, 11aS)-11-hydroxy-7-methoxy-8-((5-(((S)-7-methoxy-2-methyl-5-oxo-5, 11a-dihydr

SMILES

CC1=CN2C(C1)C=NC3=CC(=C(C=C3C2=O)OC)OCCCCCOC4=C(C=C5C(=C4)N(C(C6CC(=CN6C5=O)C)O)C(=O)OCC7=CC=C(C=C7)NC(=O)C(C)NC(=O)C(C(C)C)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN8C(=O)C=CC8=O)OC

Molecular Formula

C75H101N9O23

CAS Number

1595275-62-9

Formula Weight

1496.67

NMR

Consistent with structure

Pathway

Antibody Drug Conjugates (ADC)

Product Categories/Family for Tesirine biochemical

Antibody Drug Conjugates (ADC)

Product References and Citations for Tesirine biochemical

1. Tiberghien AC, et al. ACS Med Chem Lett. 2016 May 24; 7 (11):983-987.
2. Cancer Discov. 2015 Dec; 5 (12):OF4. doi: 10.1158/2159-8290.CD-NB2015-144.
3. Rudin CM, et al. Lancet Oncol. 2017 Jan; 18 (1):42-51.

Other Notes

Small volumes of Tesirine biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tesirine purchase

MBS3602277 is a biochemical targeting Tesirine.