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GMI-1271

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603000

A novel specific glycomimetic E-Selectin antagonist with Kd of 0.46 uM, IC50 of 1.75 uM. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GMI-1271, Biochemical
Full Product Name
GMI-1271
Product Synonym Names
GMI1271; Uproleselan sodium
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
1326.508
Target
Selectin
Receptor
Selectin
Chemical Name
4, 7, 10, 13, 16, 19, 22, 25, 28, 31, 34, 37-Dodecaoxaoctatriacontanamide, N-[2-[[[(1R, 3R, 4R, 5S)-3-[[2-(acetylamino)-3-O-[(1S)-1-carboxy-2-cyclohexylethyl]-2-deoxy-b-D-galactopyranosyl]oxy]-4-[(6-deoxy-a-L-galactopyranosyl)oxy]-5-ethylcyclohexyl]carbonyl]amino]ethyl
SMILES
O=C([O-])[C@@H](O[C@@H]1[C@@H](NC(C)=O)[C@H](O[C@H]2[C@H](O[C@H]3[C@H]([C@@H]([C@@H]([C@H](CO)O3)O)O)O)[C@@H](CC)C[C@@H](C(NCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)C2)O[C@H](CO)[C@@H]1O)CC4CCCCC4.[Na+]
Molecular Formula
C60H108N3NaO27
CAS Number
1914993-95-5

Product Categories/Family for GMI-1271 biochemical

Blood cancer; Cytoskeleton/Cell Adhesion Molecules; Cancer

Structure of GMI-1271 biochemical

GMI-1271 Biochemical – Cat# MBS3603000

Product References and Citations for GMI-1271 biochemical

1. Price TT, et al. Mol Cell Oncol. 2016 Jul 26; 4 (4):e1214771.
2. Culmer DL, et al. Thromb Haemost. 2017 Jun 2; 117 (6):1171-1181.
3. Natoni A, et al. Leukemia. 2017 Apr 25. doi: 10.1038/leu.2017.123.
4. Dutta P, et al. Arterioscler Thromb Vasc Biol. 2016 Sep; 36 (9):1802-8.

Other Notes

Small volumes of GMI-1271 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GMI-1271 purchase

MBS3603000 is a biochemical targeting GMI-1271.
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