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AIFM3 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421874

MBS421874 is an antibody targeting AIFM3. Also known as Goat anti-AIFM3 Antibody. Reactive in Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow. Host: Goat. More details

$305 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AIFM3, Polyclonal Antibody
Full Product Name
Goat anti-AIFM3 Antibody
Product Gene Name
Product Synonym Names
AIFM3; apoptosis-inducing factor, mitochondrion-associated, 3; AIFL; FLJ30473; apoptosis-inducing factor like; AIFL antibody; apoptosis-inducing factor like antibody; apoptosis-inducing factor; mitochondrion-associated; 3 antibody; FLJ30473 antibody; AIFM3 antibody
Immunogen Sequence
TARHFHTEER LSTPH
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
AIFM3 peptide (MBS426538) is used for blocking the activity of AIFM3 antibody (MBS421874)
Molecular Weight
65,966 Da
Immunogen
Peptide with sequence C-TARHFHTEERLSTPH, from the internal region of the protein sequence according to NP_653305.1; NP_001018070.1; NP_001139760.1.
Epitope
Internal region
Note
This antibody is expected to recognize all isoforms (NP_653305.1; NP_001018070.1, NP_001139760.1).
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-AIFM3 antibody
Peptide ELISA (EIA)
Application Notes for anti-AIFM3 antibody
Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Preliminary experiments in Human Colon, Kidney and Liver lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).

Other Notes

Small volumes of anti-AIFM3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AIFM3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
apoptosis-inducing factor 3 isoform 1
NCBI Official Synonym Full Names
apoptosis inducing factor, mitochondria associated 3
NCBI Official Symbol
AIFM3
NCBI Official Synonym Symbols
AIFL
UniProt Protein Name
Apoptosis-inducing factor 3
UniProt Synonym Protein Names
Apoptosis-inducing factor-like protein
UniProt Gene Name
AIFM3
UniProt Synonym Gene Names
AIFL
UniProt Entry Name
AIFM3_HUMAN
NCBI Protein Information
apoptosis-inducing factor 3

UniProt Comments for AIFM3

AIFM3: Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential. Belongs to the FAD-dependent oxidoreductase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.-.-.-; Endoplasmic reticulum; Oxidoreductase; Apoptosis; Mitochondrial

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: endoplasmic reticulum; mitochondrial inner membrane; mitochondrion; nucleus

Molecular Function: 2 iron, 2 sulfur cluster binding; FAD binding; metal ion binding; oxidoreductase activity

Biological Process: cell redox homeostasis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-AIFM3 antibody

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