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SEPT6 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421879

MBS421879 is an antibody targeting SEPT6. Also known as Goat anti-SEPT6 Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human, Cow, Dog. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SEPT6, Polyclonal Antibody
Full Product Name
Goat anti-SEPT6 Antibody
Product Gene Name
Product Synonym Names
SEPT6; septin 6; KIAA0128; MGC16619; MGC20339; SEP2; SEPT2; septin 2; SEPT6 antibody; septin 6 antibody; KIAA0128 antibody; MGC16619 antibody; MGC20339 antibody; SEP2 antibody; SEPT2 antibody; septin 2 antibody
Immunogen Sequence
DEVNAFKQRK TA
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human, Cow, Dog
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Matching Pairs
Unconjugated Antibody: SEPT6 (MBS421879)
Biotin Conjugated Antibody: SEPT6 (MBS423734)
Antibody/Peptide Pairs
SEPT6 peptide (MBS425573) is used for blocking the activity of SEPT6 antibody (MBS421879)
Molecular Weight
49,167 Da
OMIM
300683
Immunogen
Peptide with sequence C-DEVNAFKQRKTA, from the internal region of the protein sequence according to NP_665798.1; NP_055944.2; NP_665801.1.
Epitope
Internal region
Note
This antibody is expected to recognize the reported isoforms NP_665798.1, NP_055944.2 and NP_665801.1. Reported variants NP_665799.1 and NP_665798.1 represent identical protein.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-SEPT6 antibody
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SEPT6 antibody
Peptide ELISA: Antibody detection limit dilution 1: 4000.
Immunohistochemistry: In paraffin embedded Human Tonsil shows specific staining in dividing cells just outside a germinal centre. Recommended concentration, 3-5ug/ml.
Western Blot: Approx 50kDa band observed in Human Testis, Thyroid Gland and MOLT4 cell lysates (calculated MW of 49.7kDa according to NP_055944.2). Recommended concentration: 0. 03-1ug/ml.

Western Blot (WB) of anti-SEPT6 antibody

(1ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-SEPT6 Polyclonal Antibody – Cat# MBS421879

Immunohistochemistry (IHC) of anti-SEPT6 antibody

(3.8ug/ml) staining of paraffin embedded Human Tonsil. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Goat Anti-SEPT6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS421879

Other Notes

Small volumes of anti-SEPT6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SEPT6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
septin-6 isoform A
NCBI Official Synonym Full Names
septin 6
NCBI Official Symbol
SEPT6
NCBI Official Synonym Symbols
SEP2; SEPT2
UniProt Protein Name
Septin-6
UniProt Gene Name
SEPT6
UniProt Synonym Gene Names
KIAA0128; SEP2
UniProt Entry Name
SEPT6_HUMAN
NCBI Protein Information
septin-6

NCBI Summary for SEPT6

This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]
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UniProt Comments for SEPT6

SEPT6: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. Belongs to the septin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; Cytoskeletal

Chromosomal Location of Human Ortholog: Xq24

Cellular Component: cleavage furrow; midbody; nerve terminal; spindle; synaptic vesicle

Molecular Function: GTP binding; protein binding

Biological Process: cytokinesis; viral reproduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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