• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ASIC1 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS423577

MBS423577 is an antibody targeting ASIC1. Also known as Goat anti-ASIC1 Antibody. Reactive in Tested: Mouse; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ASIC1, Polyclonal Antibody
Full Product Name
Goat anti-ASIC1 Antibody
Product Gene Name
Product Synonym Names
ASIC1; acid-sensing (proton-gated) ion channel 1; ACCN2; ASIC; BNaC2; Cation channel, amiloride-sensitive, neuronal, 2; acid-sensing ion channel 1; acid-sensing ion channel 1a protein; amiloride-sensitive cation channel 2, neuronal; brain sodium channel 2; ASIC1 antibody; acid-sensing (proton-gated) ion channel 1 antibody; ACCN2 antibody; ASIC antibody; BNaC2 antibody; Cation channel; amiloride-sensitive; neuronal; 2 antibody; acid-sensing ion channel 1 antibody; acid-sensing ion channel 1a protein antibody; amiloride-sensitive cation channel 2; neuronal antibody; brain sodium channel 2 antibody
Immunogen Sequence
NILPHHPARG T
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Mouse; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
ASIC1 peptide (MBS428652) is used for blocking the activity of ASIC1 antibody (MBS423577)
Molecular Weight
62,700 Da
OMIM
602866
Immunogen
Peptide with sequence C-NILPHHPARGT, from the C Terminus of the protein sequence according to NP_064423.2; NP_001086.2; NP_001243759.1.
Epitope
C Terminus
Note
This antibody is expected to recognize all reported isoforms (NP_064423.2; NP_001086.2; NP_001243759.1).
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-ASIC1 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-ASIC1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Approx 70kDa band observed in Mouse fetal Brain lysates (calculated MW of 64.8kDa according to NP_064423.2). Recommended concentration: 0.3-1ug/ml.

Western Blot (WB) of anti-ASIC1 antibody

(0.3ug/ml) staining of Mouse fetal Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-ASIC1 Polyclonal Antibody – Cat# MBS423577

Other Notes

Small volumes of anti-ASIC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ASIC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
acid-sensing ion channel 1 isoform a
NCBI Official Synonym Full Names
acid sensing ion channel subunit 1
NCBI Official Symbol
ASIC1
NCBI Official Synonym Symbols
ASIC; ACCN2; BNaC2
UniProt Protein Name
Acid-sensing ion channel 1
UniProt Synonym Protein Names
Amiloride-sensitive cation channel 2, neuronal; Brain sodium channel 2; BNaC2
UniProt Gene Name
ASIC1
UniProt Synonym Gene Names
ACCN2; BNAC2; ASIC1; BNaC2
UniProt Entry Name
ASIC1_HUMAN
NCBI Protein Information
acid-sensing ion channel 1

NCBI Summary for ASIC1

This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]
Show more

UniProt Comments for ASIC1

ASIC1 iso1: non-voltage-gated amiloride-sensitive cation channel permeable for sodium, potassium and lithium. A member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Expressed in most if not all brain neurons.

Protein type: Channel, cation; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ion channel

Chromosomal Location of Human Ortholog: 12q12

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: amiloride-sensitive sodium channel activity; protein binding

Biological Process: response to pH; sensory perception of sour taste; signal transduction; transport
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000