SDF-1alpha Human Active Protein

Description: Recombinant human SDF-1alpha produced in E Coli is a single, non-glycosylated, polypeptide chain containing 68 amino acids and having a molecular mass of approximately 8 kDa.
Introduction: The stromal cell-derived factor 1 (SDF-1) also known as C-X-C motif chemokine 12 (CXCL12) is a chemokine protein that in humans is encoded by the CXCL12 gene. SDF-1 is produced in two forms, SDF-1alpha/CXCL12a and SDF-1beta/CXCL12b, by alternate splicing of the same gene.
SDF-1 functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4 (CXCR4), and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections.

Small volumes of SDF-1alpha active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS434179 is an active protein targeting SDF-1alpha. Also known as Human SDF-1alpha (CXCL12-1a), E Coli. Host: E Coli.