Interleukin 12b (IL12B) ELISA Kit for Human

Name: Human IL12B ELISA Kit; Interleukin 12b; MyBioSource
Brand: MyBioSource
SKU: MBS456092
Price: 440 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS456092

MBS456092 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interleukin 12B (IL12B) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$440 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Interleukin 12B (IL12B), ELISA Kit

Full Product Name

Human Interleukin 12B (IL12B) ELISA Kit

Product Gene Name

IL12B elisa kit

Product Synonym Names

IL12A

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Detection Range

31.25-2000pg/mL

Sensitivity

11.84pg/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

37,169 Da

OMIM

M65272 mRNA

3D Structure

ModBase 3D Structure for P29460

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of IL12B elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL12B. It may not necessarily be applicable to this product.

NCBI GI #

24497438

NCBI GeneID

3593

NCBI Accession #

NP_002178.2

UniProt Primary Accession #

P29460

UniProt Related Accession #

P29460

GenBank Nucleotide #

NM_002187.2

NCBI Official Full Name

interleukin-12 subunit beta

NCBI Official Synonym Full Names

interleukin 12B

NCBI Official Symbol

IL12B

NCBI Official Synonym Symbols

CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B

UniProt Protein Name

Interleukin-12 subunit beta

UniProt Synonym Protein Names

Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40; NK cell stimulatory factor chain 2; NKSF2

Protein Family

Interleukin

UniProt Gene Name

IL12B

UniProt Synonym Gene Names

NKSF2; IL-12B; CLMF p40; NKSF2

NCBI Protein Information

interleukin-12 subunit beta

NCBI Summary for IL12B

This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008]

UniProt Comments for IL12B

Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.

Research Articles on IL12B

1. analysis of cytokine gene polymorphisms suggests that IL-12 gene may play impact on specific pathogenesis of ophthalmopathy in Korean children with early onset autoimmune thyroid disease.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IL12B elisa kit

Reference Product	PubMed Publications
IL12A elisa kit	>69 publications with IL12B and IL12A
IL6 elisa kit	>54 publications with IL12B and IL6
IL4 elisa kit	>48 publications with IL12B and IL4
IL12RB1 elisa kit	>47 publications with IL12B and IL12RB1
JUN elisa kit	>39 publications with IL12B and JUN
IL23A elisa kit	>37 publications with IL12B and IL23A
IL1B elisa kit	>35 publications with IL12B and IL1B
IL12RB2 elisa kit	>16 publications with IL12B and IL12RB2
NOS2 elisa kit	>12 publications with IL12B and NOS2
FOS elisa kit	>1 publications with IL12B and FOS

Pathways associated with IL12B elisa kit

Products by Pathway	Pathway Diagram
African Trypanosomiasis Pathway antibodies	African Trypanosomiasis Pathway Diagram
African Trypanosomiasis Pathway antibodies	African Trypanosomiasis Pathway Diagram
Allograft Rejection Pathway antibodies	Allograft Rejection Pathway Diagram
Allograft Rejection Pathway antibodies	Allograft Rejection Pathway Diagram
Allograft Rejection Pathway antibodies	Allograft Rejection Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Aryl Hydrocarbon Receptor Pathway antibodies	Aryl Hydrocarbon Receptor Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram

Diseases associated with IL12B elisa kit

Disease Name	Pubmed Publications
Psoriasis Antibodies	>85 publications with IL12B and Psoriasis
Inflammation Antibodies	>77 publications with IL12B and Inflammation
Necrosis Antibodies	>62 publications with IL12B and Necrosis
Lung Diseases Antibodies	>37 publications with IL12B and Lung Diseases
Crohn Disease Antibodies	>36 publications with IL12B and Crohn Disease
Arthritis, Psoriatic Antibodies	>28 publications with IL12B and Arthritis, Psoriatic
Liver Diseases Antibodies	>25 publications with IL12B and Liver Diseases
Colitis, Ulcerative Antibodies	>24 publications with IL12B and Colitis, Ulcerative
Disease Models, Animal Antibodies	>21 publications with IL12B and Disease Models, Animal
Asthma Antibodies	>17 publications with IL12B and Asthma

Organs/Tissues associated with IL12B elisa kit

Organ/Tissue Name	Pubmed Publications
Mixed Antibodies	>4 publications with IL12B and Mixed