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SOX-1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS460379

The SOX1 is a transcription factor, a member of the SRY-related HMG-box (SOX) family involved in the regulation of embryonic development and in the determination of cell fate. SOX1 is expressed in the developing brain. SOX1 is related to the HMG box of family… More details

$355 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SOX-1, Polyclonal Antibody
Full Product Name
Rabbit anti SOX-1 Polyclonal Antibody
Product Gene Name
Product Synonym Names
SRY (sex determining region Y)-box 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purity/Purification
Purified by Epitope Affinity Purification
Specificity
This antibody recognizes ~40 kDa of human SOX-1 protein. It also reacts with mouse. The other species are not tested.
Preparation and Storage
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C. The antibodies can be stored at 2 degree C - 8 degree C for one month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Molecular Weight
39,053 Da
3D Structure
ModBase 3D Structure for P53783
Preparation
A synthetic peptide derived from N-terminus of Human SOX-1 protein. This sequence is identical among human and mouse.
Applications Tested/Suitable for anti-SOX-1 antibody
ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-SOX-1 antibody
ELISA: 0.01-0.1 ug/ml
Flow Cytometry: 5-10 ug/ml
Immunohistochemistry: 2-10 ug/ml
Immunoprecipitation: 2-5 ug/ml
Western Blot: 0.1-1 ug/ml

Product References and Citations for anti-SOX-1 antibody

Alcock J, Lowe J, England T, Bath P, Sottile V. Expression of Sox1, Sox2 and Sox9 is maintained in adult human cerebellar cortex. Neurosci Lett. 2009 Jan 30;450 (2):114-6.

Other Notes

Small volumes of anti-SOX-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SOX-1 purchase

MBS460379 is an antibody targeting SOX-1. Also known as Rabbit anti SOX-1 Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SOX-1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
SOX1 protein
NCBI Official Synonym Full Names
SRY (sex determining region Y)-box 1
NCBI Official Symbol
Sox1
NCBI Official Synonym Symbols
Sox-1; BB176347
UniProt Protein Name
Transcription factor SOX-1
Protein Family
UniProt Gene Name
Sox1
UniProt Synonym Gene Names
Sox-1
NCBI Protein Information
transcription factor SOX-1

UniProt Comments for SOX-1

SOX1: Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Mainly expressed in the developing central nervous system.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 8 A1.1|8 5.73 cM

Cellular Component: nucleus

Molecular Function: DNA binding; sequence-specific DNA binding

Biological Process: forebrain development; forebrain neuron development; forebrain neuron differentiation; lens morphogenesis in camera-type eye; neuron migration; positive regulation of transcription from RNA polymerase II promoter; ventral spinal cord interneuron specification
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SOX-1 antibody

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