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IL-5 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS488518

Describes the original generation of this antibody, and its characterisation and use in ELISA.Recombinant monoclonal antibody to IL-5. Manufactured using our Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 2E3. More details

$635 / 0.2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL-5, Monoclonal Antibody
Full Product Name
Anti-IL-5 [2E3], Rabbit IgG, Kappa
Product Gene Name
Product Synonym Names
interleukin 5; IL5; IL 5; Eosinophil differentiation factor
Clonality
Monoclonal
Isotype
Rabbit IgG, Kappa
Clone Number
2E3
Host
Mouse
Species Reactivity
Human
Form/Format
PBS with 0.02% Proclin 300
Purity/Purification
Protein A affinity purified
Concentration
1mg/ml (lot specific)
Specificity
The antibody is specific for human rIL-5, and does not cross-react with human rIL-1alpha, rIL-lbeta, rIL-4, rIL-8, rM-CSF, or rTGF-alpha.
Preparation and Storage
Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
3D Structure
ModBase 3D Structure for C9JQP9
Animal-free Manufacturing Platform
The recombinant antibody is manufactured using a recombinant, mammalian HEK293-based expression platform. The manufacturing platform is animal-free and animal component-free.
Antibody Type
Recombinant Antibody
Immunogen
This antibody was raised by immunising CAF1 mice with human recombinant IL-5.
Chimeric Use Statement
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Product Categories/Family for anti-IL-5 antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-IL-5 antibody
Neutralising, ELISA (EIA)
Application Notes for anti-IL-5 antibody
This antibody has been show to inhibit the binding of human rIL-5 to the alpha chain of the IL-5 receptor (Ames et al, 1995). This antibody inhibits the proliferation of murine B13 cells in response to human IL-5 (Ames et al, 1995).Neutralising antibodies against IL-5 represent a potential therapeutic strategy for the treatment of eosinophilia. The specificity of this antibody for human IL-5 has been confirmed in ELISA analysis (Ames et al, 1995).

Product References and Citations for anti-IL-5 antibody

Ames et al.; J. Immunol. 154 (12), 6355-6364 (1995). OriginPubPMID: 7759873

Other Notes

Small volumes of anti-IL-5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL-5 purchase

MBS488518 is an antibody targeting IL-5. Also known as Anti-IL-5 [2E3], Rabbit IgG, Kappa. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-5. It may not necessarily be applicable to this product.

UniProt Primary Accession #

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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