ERp72 Recombinant Protein

Name: ERp72 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS565957
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS565957

Endoplasmic reticulum protein (ERp) 72 is a member of the protein disulfide isomerase (PDI) family that is localized to the endoplasmic reticulum. It contains three repeats of the thioredoxin-like regions that is postulated to represent three independently… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ERp72, Recombinant Protein

Full Product Name

ERp72 (human), (recombinant) (His-tag)

Product Gene Name

ERp72 recombinant protein

Host

E Coli

Form/Format

Liquid. In 50mM TRIS, pH7.5, containing 150mM sodium chloride and 1mM EDTA

Purity/Purification

>=85% (SDS-PAGE; Western blot)
Purified by multi-step chromatography

Preparation and Storage

For long term storage, store at -80 degree C
Shipping: Shipped on Dry Ice

Molecular Weight

645

3D Structure

ModBase 3D Structure for P13667

Source Note

Human ERp72 is fused at the N-terminus to a His-tag

Product Categories/Family for ERp72 recombinant protein

Cellular Analysis; Oxidative Stress; Proteostasis; Protein Synthesis & Folding

Applications Tested/Suitable for ERp72 recombinant protein

Western Blot (WB), Activity assay

Application Notes for ERp72 recombinant protein

Activity Assay: >90U/mg
WB: 25ng, colorimetric

Other Notes

Small volumes of ERp72 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ERp72 purchase

MBS565957 is a recombinant protein targeting ERp72. Also known as ERp72 (human), (recombinant) (His-tag). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for ERp72. It may not necessarily be applicable to this product.

NCBI GI #

119530

NCBI GeneID

9601

NCBI Accession #

P13667.2

UniProt Primary Accession #

P13667

UniProt Secondary Accession #

Q549T6; A8K4K6

UniProt Related Accession #

P13667

NCBI Official Full Name

Protein disulfide-isomerase A4

NCBI Official Synonym Full Names

protein disulfide isomerase family A, member 4

NCBI Official Symbol

PDIA4

NCBI Official Synonym Symbols

ERP70; ERP72; ERp-72

UniProt Protein Name

Protein disulfide-isomerase A4

UniProt Synonym Protein Names

Endoplasmic reticulum resident protein 70; ER protein 70; ERp70; Endoplasmic reticulum resident protein 72; ER protein 72; ERp-72; ERp72

UniProt Gene Name

PDIA4

UniProt Synonym Gene Names

ERP70; ERP72; ER protein 70; ERp70; ER protein 72; ERp-72; ERp72

UniProt Entry Name

PDIA4_HUMAN

NCBI Protein Information

protein disulfide-isomerase A4; ER protein 70; ER protein 72; protein disulfide isomerase-associated 4; endoplasmic reticulum resident protein 70; endoplasmic reticulum resident protein 72; protein disulfide isomerase related protein (calcium-binding prot

UniProt Comments for ERp72

PDIA4: Part a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX. Belongs to the protein disulfide isomerase family.

Protein type: EC 5.3.4.1; Isomerase; Chaperone; Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 7q35

Cellular Component: cell surface; endoplasmic reticulum; endoplasmic reticulum lumen; melanosome

Molecular Function: protein binding; protein disulfide isomerase activity

Biological Process: protein folding; cell redox homeostasis; protein secretion

Research Articles on ERp72

1. the faster migrating Tg adduct C primarily engages the CaBP1/P5 oxidoreductase, whereas the slower migrating Tg adduct A primarily engages ERp72.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ERp72 recombinant protein

Reference Product	PubMed Publications
PDIA6 recombinant protein	>5 publications with ERp72 and PDIA6
HSPA5 recombinant protein	>4 publications with ERp72 and HSPA5
CALR recombinant protein	>1 publications with ERp72 and CALR
ERO1LB recombinant protein	>1 publications with ERp72 and ERO1LB

Pathways associated with ERp72 recombinant protein

Products by Pathway	Pathway Diagram
Protein Processing In Endoplasmic Reticulum Pathway antibodies	Protein Processing In Endoplasmic Reticulum Pathway Diagram
Protein Processing In Endoplasmic Reticulum Pathway antibodies	Protein Processing In Endoplasmic Reticulum Pathway Diagram
Thyroid Hormone Synthesis Pathway antibodies	Thyroid Hormone Synthesis Pathway Diagram
Thyroid Hormone Synthesis Pathway antibodies	Thyroid Hormone Synthesis Pathway Diagram
Vibrio Cholerae Infection Pathway antibodies	Vibrio Cholerae Infection Pathway Diagram
Vibrio Cholerae Infection Pathway antibodies	Vibrio Cholerae Infection Pathway Diagram

Diseases associated with ERp72 recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>3 publications with ERp72 and Inflammation
Adenocarcinoma Antibodies	>2 publications with ERp72 and Adenocarcinoma
Liver Diseases Antibodies	>2 publications with ERp72 and Liver Diseases
Nervous System Diseases Antibodies	>1 publications with ERp72 and Nervous System Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with ERp72 and Carcinoma, Hepatocellular
Liver Neoplasms Antibodies	>1 publications with ERp72 and Liver Neoplasms

Organs/Tissues associated with ERp72 recombinant protein

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>3 publications with ERp72 and Liver
Muscle Antibodies	>2 publications with ERp72 and Muscle
Brain Antibodies	>2 publications with ERp72 and Brain
Lung Antibodies	>2 publications with ERp72 and Lung
Vascular Antibodies	>1 publications with ERp72 and Vascular
Heart Antibodies	>1 publications with ERp72 and Heart
Blood Antibodies	>1 publications with ERp72 and Blood
Pancreas Antibodies	>1 publications with ERp72 and Pancreas
Eye Antibodies	>1 publications with ERp72 and Eye
Intestine Antibodies	>1 publications with ERp72 and Intestine