PRIMA-1Met Inhibitor

Name: PRIMA-1Met Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5750534
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750534

PRIMA-1MET restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells. PRIMA-1MET also targets the selenoprotein thioredoxin reductase 1 (TrxR1), a key regulator of cellular redox balance. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PRIMA-1Met, Inhibitor

Full Product Name

PRIMA-1Met

Product Gene Name

PRIMA-1Met, inhibitor

Product Synonym Names

p53; Autophagy

Form/Format

POWDER

Purity/Purification

99.6%

Preparation and Storage

Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C

Molecular Weight

199.25

CAS Number

5291-32-7

Formula

C10H17NO3

Smiles

O=C2C1CCN(CC1)C2(COC)CO

Solubility

DMSO: 1.99 mg/mL (10 mM)

Pathways

Apoptosis

Receptor

p53 activator; TrxR1 inhibitor

Product Remark

For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for PRIMA-1Met, inhibitor

Cancer

Product References and Citations for PRIMA-1Met, inhibitor

1. Peng X,etal.APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase.Cell Death Dis. 2013 Oct 24; 4:e881.

Other Notes

Small volumes of PRIMA-1Met, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PRIMA-1Met purchase

MBS5750534 is an inhibitor targeting PRIMA-1Met.