DBCO-S-S-PEG3-biotin Inhibitor

Name: DBCO-S-S-PEG3-biotin Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5754770
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754770

DBCO-S-S-PEG3-biotin is a cleavable reagent for introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP to remove the… More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

DBCO-S-S-PEG3-biotin, Inhibitor

Full Product Name

DBCO-S-S-PEG3-biotin

Product Gene Name

DBCO-S-S-PEG3-biotin, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

869.12

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C42H56N6O8S3

SMILES

O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(NCCSSCCC(NCCOCCOCCOCCNC(CCCC[C@H]4[C@](NC5=O)([H])[C@](N5)([H])CS4)=O)=O)=O

CAS Number

1430408-09-5

Target & IC50

PEGs

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Product Categories/Family for DBCO-S-S-PEG3-biotin, inhibitor

PROTAC

Product References and Citations for DBCO-S-S-PEG3-biotin, inhibitor

An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Other Notes

Small volumes of DBCO-S-S-PEG3-biotin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DBCO-S-S-PEG3-biotin purchase

MBS5754770 is an inhibitor targeting DBCO-S-S-PEG3-biotin.