Rabbit Anti-AKIRIN2 Polyclonal Antibody – Cat# MBS621733

Western blot analysis of Akirin2 in Human Brain tissue lysate with Akirin2 antibody at 0.5 ug/ml in (A) the absence and (B) the presence ofblocking peptide.

AKIRIN2 Antibody – Rabbit Polyclonal

Name: AKIRIN2 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS621733
Price: 850 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS621733

The highly conserved, nuclear-localized Akirin1 and Akirin2 proteins critically regulate the transcription of NF-kappaB-dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-kappaB pathways. Akirin1 is… More details

$850 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Akirin2, IN2, Polyclonal Antibody

Full Product Name

Akirin2, IN2 (C6orf166, chromosome 6 open reading frame 166, dJ486L4.2, FBI1, FLJ10342, Protein C6orf166, Uncharacterized protein C6orf166)

Product Gene Name

anti-AKIRIN2 antibody

Product Synonym Names

Anti -Akirin2, IN2 (C6orf166, chromosome 6 open reading frame 166, dJ486L4.2, FBI1, FLJ10342, Protein C6orf166, Uncharacterized protein C6orf166)

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Supplied as a liquid in PBS, 0.02% sodium azide.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes human Akirin2. Species Crossreactivity: Mouse and rat.

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

22,496 Da

Chromosome Location

Chromosome: 6; NC_000006.11 (88384578..88411985, complement). Location: 6q15

3D Structure

ModBase 3D Structure for Q53H80

Immunogen

Synthetic peptide corresponding to 15aa from near the center of the human Akirin2.

Positive Control

Human Brain Tissue Lysate

Product Categories/Family for anti-AKIRIN2 antibody

Antibodies; Abs to Proteins

Applications Tested/Suitable for anti-AKIRIN2 antibody

Western Blot (WB)

Application Notes for anti-AKIRIN2 antibody

Suitable for use in Western Blot.
Dilution: Western Blot: 0.5ug/ml

Other Notes

Small volumes of anti-AKIRIN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AKIRIN2 purchase

MBS621733 is an antibody targeting AKIRIN2. Also known as Akirin2, IN2 (C6orf166, chromosome 6 open reading frame 166, dJ486L4.2, FBI1, FLJ10342, Protein C6orf166, Uncharacterized protein C6orf166). Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AKIRIN2. It may not necessarily be applicable to this product.

NCBI GI #

14149718

NCBI GeneID

55122

NCBI Accession #

NP_060534.1

UniProt Primary Accession #

Q53H80

UniProt Secondary Accession #

Q9BQB1

UniProt Related Accession #

Q53H80; Q9NW35

GenBank Nucleotide #

NM_018064.3

NCBI Official Full Name

akirin-2

NCBI Official Synonym Full Names

akirin 2

NCBI Official Symbol

AKIRIN2

NCBI Official Synonym Symbols

FBI1; C6orf166; FLJ10342; dJ486L4.2

UniProt Protein Name

Akirin-2

Protein Family

Akirin

UniProt Gene Name

AKIRIN2

UniProt Synonym Gene Names

C6orf166

UniProt Entry Name

AKIR2_HUMAN

NCBI Protein Information

akirin-2; OTTHUMP00000016836; fourteen-three-three beta interactant 1

UniProt Comments for AKIRIN2

AKIRIN2: Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1. Belongs to the akirin family.

Protein type: Transcription regulation; Cell cycle regulation

Chromosomal Location of Human Ortholog: 6q15

Cellular Component: transcriptional repressor complex; nucleus

Molecular Function: enzyme binding

Biological Process: embryonic development; transcription, DNA-dependent; positive regulation of cell proliferation; innate immune response; positive regulation of interleukin-6 production; positive regulation of transcription from RNA polymerase II promoter; response to lipopolysaccharide; negative regulation of transcription from RNA polymerase II promoter

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-AKIRIN2 antibody

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>2 publications with AKIRIN2 and Muscle