Mouse Anti-UBE3C Polyclonal Antibody – Cat# MBS645325

Western Blot analysis of UBE3C expression in transfected 293T cell line by UBE3C polyclonal antibody. Lane 1: UBE3C transfected lysate (44.44kD). Lane 2: Non-transfected lysate. Protocol Download

UBE3C Antibody – Mouse Polyclonal

Name: UBE3C Antibody; Polyclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS645325
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS645325

MBS645325 is an antibody targeting UBE3C. Also known as UBE3C (Ubiquitin-protein Ligase E3C, HectH2, KIAA0010, KIAA10). Reactive in Human. Host: Mouse. More details

$880 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

UBE3C, Polyclonal Antibody

Full Product Name

UBE3C (Ubiquitin-protein Ligase E3C, HectH2, KIAA0010, KIAA10)

Product Gene Name

anti-UBE3C antibody

Product Synonym Names

Anti -UBE3C (Ubiquitin-protein Ligase E3C, HectH2, KIAA0010, KIAA10)

Immunogen Sequence

MFSFEGDFKT RPKVSLGGAS RKYSIQRSAF DRCATLSQSG GAFPIANGPN LTLLVRQLLF FYKQNEDSKR LIWLYQNLIK HSSLFVKQLD GSERLTCLFQ IKRLMSLCCR LLQNCNDDSL NVALPMRMLE VFSSENTYLP VLQDASYVVS VIEQILHYMI HNGYYRSLYL LINSKLPSSI EYSDLSRVPI AKILLENVLK PLHFTYNSCP EGARQQVFTA FTEEFLAAPF TDQIFHFIIP ALADAQTVFP YEPFLNALLL IESRCSRKSG GAPWLFYFVL TVGENYLGAL SEEGLLVYLR VLQTFLSQLP VSPASASCHD SASDSEEESE EADKPSSPED GRLSVSYITE ECLKKLDTKQ QTNTLLNLVW RDSASEEVFT TMASVCHTLM VQHRMMVPKV RVYK

Clonality

Polyclonal

Isotype

IgG

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human UBE3C.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

123,923 Da

Chromosome Location

Chromosome: 7; NC_000007.13 (156931655..157062066). Location: 7q36.3

OMIM

614454

3D Structure

ModBase 3D Structure for Q15386

Immunogen

Full length human UBE3C, aa1-404 (AAH26241.1).

Product Categories/Family for anti-UBE3C antibody

Antibodies; Abs to Ubiquitin

Applications Tested/Suitable for anti-UBE3C antibody

Western Blot (WB)

Application Notes for anti-UBE3C antibody

Suitable for use in Western Blot.

Other Notes

Small volumes of anti-UBE3C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for UBE3C. It may not necessarily be applicable to this product.

NCBI GI #

187960100

NCBI GeneID

9690

NCBI Accession #

NP_055486.2

UniProt Primary Accession #

Q15386

UniProt Secondary Accession #

Q8TC15; Q96CR4; Q9UDU3; A4D235; A6NCP3

UniProt Related Accession #

Q15386

GenBank Nucleotide #

NM_014671.2

NCBI Official Full Name

ubiquitin-protein ligase E3C

NCBI Official Synonym Full Names

ubiquitin protein ligase E3C

NCBI Official Symbol

UBE3C

NCBI Official Synonym Symbols

HECTH2

UniProt Protein Name

Ubiquitin-protein ligase E3C

UniProt Synonym Protein Names

HectH2

Protein Family

Ubiquitin-protein ligase

UniProt Gene Name

UBE3C

UniProt Synonym Gene Names

KIAA0010; KIAA10

UniProt Entry Name

UBE3C_HUMAN

NCBI Protein Information

ubiquitin-protein ligase E3C; ubiquitin-protein isopeptide ligase (E3)

UniProt Comments for UBE3C

UBE3C: E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 6.3.2.-; Ligase; Ubiquitin conjugating system; EC 6.3.2.19; Ubiquitin ligase

Chromosomal Location of Human Ortholog: 7q36.3

Cellular Component: proteasome complex; cytoplasm; intracellular; nucleus

Molecular Function: protein binding; ubiquitin-protein ligase activity; ligase activity

Biological Process: protein polyubiquitination; protein ubiquitination during ubiquitin-dependent protein catabolic process

Research Articles on UBE3C

1. Our findings provide evidence that variations in UBE3C are potent genetic markers of nasal polyps development in Korean asthmatics.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-UBE3C antibody

Reference Product	PubMed Publications
UBC antibody	>1 publications with UBE3C and UBC

Pathways associated with anti-UBE3C antibody

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Antigen Processing: Ubiquitination & Proteasome Degradation Pathway antibodies	Antigen Processing: Ubiquitination & Proteasome Degradation Pathway Diagram
Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies	Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Ubiquitin Mediated Proteolysis Pathway antibodies	Ubiquitin Mediated Proteolysis Pathway Diagram
Ubiquitin Mediated Proteolysis Pathway antibodies	Ubiquitin Mediated Proteolysis Pathway Diagram

Diseases associated with anti-UBE3C antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>1 publications with UBE3C and Inflammation
Cardiovascular Diseases Antibodies	>1 publications with UBE3C and Cardiovascular Diseases

Organs/Tissues associated with anti-UBE3C antibody

Organ/Tissue Name	Pubmed Publications
Spinal Cord Antibodies	>1 publications with UBE3C and Spinal Cord
Bone Antibodies	>1 publications with UBE3C and Bone
Muscle Antibodies	>1 publications with UBE3C and Muscle