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HSD17B2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS832827

MBS832827 is an antibody targeting HSD17B2. Also known as HSD17B2 antibody. Host: Mouse. Mouse monoclonal HSD17B2 antibody More details

$1625 / 0.1 mL +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HSD17B2, Monoclonal Antibody
Full Product Name
HSD17B2 antibody
Product Gene Name
anti-HSD17B2 antibody
Product Synonym Names
Monoclonal HSD17B2; Anti-HSD17B2; EDH17B2; HSD17; SDR9C2; HSD17B2; HSDB2 17; HSDB2-17
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4F10
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
HSD17B2 antibody was purified by affinity chromatography.
Concentration
0.5-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
41,836 Da
3D Structure
ModBase 3D Structure for P51658
Cross-Reactivity
Human
Immunogen
HSD17B2 antibody was raised in Mouse using full length human recombinant protein of human HSD17B2 produced in HEK293T cell as the immunogen.

Product Categories/Family for anti-HSD17B2 antibody

Hormones & Steroids
Applications Tested/Suitable for anti-HSD17B2 antibody
Flow Cytometry (FC/FACS), Western Blot (WB)
Application Notes for anti-HSD17B2 antibody
FC: 1:100
WB: 1:2000

Flow Cytometry (FC/FACS) of anti-HSD17B2 antibody

Flow Cytometric analysis of HEK293T cells transfected with either recombinant HSD17B2 protein (red) or empty vector (blue) stained using HSD17B2 antibody
Mouse Anti-HSD17B2 Monoclonal Antibody – Cat# MBS832827

Western Blot (WB) of anti-HSD17B2 antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant HSD17B2 protein (Right) or empty vector (Left) detected with HSD17B2 antibody
Mouse Anti-HSD17B2 Monoclonal Antibody, Western Blot (WB) – Cat# MBS832827

Other Notes

Small volumes of anti-HSD17B2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HSD17B2. It may not necessarily be applicable to this product.

NCBI GI #
15215149
NCBI GeneID
15486
NCBI Accession #
AAH12682.1
UniProt Primary Accession #
P51658
UniProt Secondary Accession #
O08898
UniProt Related Accession #
P51658
NCBI Official Full Name
Hsd17b2 protein
NCBI Official Synonym Full Names
hydroxysteroid (17-beta) dehydrogenase 2
NCBI Official Symbol
Hsd17b2
NCBI Official Synonym Symbols
AI194836; AI194967; AI255511
UniProt Protein Name
Estradiol 17-beta-dehydrogenase 2
UniProt Synonym Protein Names
17-beta-hydroxysteroid dehydrogenase type 2; 17-beta-HSD 2; Testosterone 17-beta-dehydrogenase (EC:1.1.1.239)
Protein Family
Estradiol 17 beta-dehydrogenase
UniProt Gene Name
Hsd17b2
UniProt Synonym Gene Names
Edh17b2; 17-beta-HSD 2
UniProt Entry Name
DHB2_MOUSE
NCBI Protein Information
estradiol 17-beta-dehydrogenase 2

UniProt Comments for HSD17B2

HSD17B2: Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH. Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Protein type: Lipid Metabolism - androgen and estrogen; Endoplasmic reticulum; Oxidoreductase; EC 1.1.1.239; EC 1.1.1.62; Membrane protein, integral

Cellular Component: membrane; intracellular membrane-bound organelle; integral to membrane

Molecular Function: estradiol 17-beta-dehydrogenase activity; oxidoreductase activity; 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity

Biological Process: response to retinoic acid; metabolic process; in utero embryonic development; androgen biosynthetic process; lipid metabolic process; estrogen biosynthetic process; steroid biosynthetic process; placenta development
Show more

Research Articles on HSD17B2

1. These results demonstrate temporal and spatial regulation of androgen receptor and 17beta-HSD 2 during the sacculo-alveolar transition period of mouse lung development suggesting control of androgen action.[17beta HSD2]

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HSD17B2 antibody

 Reference Product  PubMed Publications
 Cyp19a1 antibody  >326 publications with HSD17B2 and Cyp19a1
 Cyp17a1 antibody  >98 publications with HSD17B2 and Cyp17a1
 Srd5a2 antibody  >43 publications with HSD17B2 and Srd5a2
 Hsd3b1 antibody  >20 publications with HSD17B2 and Hsd3b1
 Srd5a1 antibody  >11 publications with HSD17B2 and Srd5a1
 Hsd3b2 antibody  >5 publications with HSD17B2 and Hsd3b2
 Akr1d1 antibody  >1 publications with HSD17B2 and Akr1d1
 Hsd3b5 antibody  >1 publications with HSD17B2 and Hsd3b5

Pathways associated with anti-HSD17B2 antibody

 Products by Pathway  Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Ovarian Steroidogenesis Pathway antibodies  Ovarian Steroidogenesis Pathway Diagram
 Ovarian Steroidogenesis Pathway antibodies  Ovarian Steroidogenesis Pathway Diagram
 Steroid Biosynthesis Pathway antibodies  Steroid Biosynthesis Pathway Diagram
 Steroid Hormone Biosynthesis Pathway antibodies  Steroid Hormone Biosynthesis Pathway Diagram
 Steroid Hormone Biosynthesis Pathway antibodies  Steroid Hormone Biosynthesis Pathway Diagram
 Biosynthesis Of Estrogens Pathway antibodies  Biosynthesis Of Estrogens Pathway Diagram

Diseases associated with anti-HSD17B2 antibody

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >230 publications with HSD17B2 and Breast Neoplasms
 Adenocarcinoma Antibodies  >70 publications with HSD17B2 and Adenocarcinoma
 Endometrial Neoplasms Antibodies  >59 publications with HSD17B2 and Endometrial Neoplasms
 Endometriosis Antibodies  >53 publications with HSD17B2 and Endometriosis
 Urogenital Abnormalities Antibodies  >49 publications with HSD17B2 and Urogenital Abnormalities
 Hyperplasia Antibodies  >44 publications with HSD17B2 and Hyperplasia
 Neoplasms, Experimental Antibodies  >41 publications with HSD17B2 and Neoplasms, Experimental
 Ovarian Neoplasms Antibodies  >38 publications with HSD17B2 and Ovarian Neoplasms
 Prostatic Neoplasms Antibodies  >35 publications with HSD17B2 and Prostatic Neoplasms
 Disease Models, Animal Antibodies  >30 publications with HSD17B2 and Disease Models, Animal

Organs/Tissues associated with anti-HSD17B2 antibody

 Organ/Tissue Name  Pubmed Publications
 Uterus Antibodies  >248 publications with HSD17B2 and Uterus
 Testis Antibodies  >175 publications with HSD17B2 and Testis
 Liver Antibodies  >173 publications with HSD17B2 and Liver
 Embryonic Tissue Antibodies  >95 publications with HSD17B2 and Embryonic Tissue
 Kidney Antibodies  >74 publications with HSD17B2 and Kidney
 Muscle Antibodies  >53 publications with HSD17B2 and Muscle
 Lung Antibodies  >24 publications with HSD17B2 and Lung
 Intestine Antibodies  >22 publications with HSD17B2 and Intestine
 Stomach Antibodies  >12 publications with HSD17B2 and Stomach
 Extraembryonic Tissue Antibodies  >6 publications with HSD17B2 and Extraembryonic Tissue
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