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AVL-292 (Spebrutinib)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS841921

Background: AVL-292 is a potent, selective inhibitor of Bruton's Tyrosine Kinase (BTK) (IC?? = 0. 5 nM) with potential antineoplastic activity. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AVL-292 (Spebrutinib), Biochemical
Full Product Name
AVL-292 (Spebrutinib)
Product Synonym Names
N-(3-((5-fluoro-2-((4-(2-methoxyethoxy)phenyl)amino)pyrimidin-4-yl)amino)phenyl)acrylamide; CC-292
Form/Format
Appearance: White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
423.44
CAS Number
1202757-89-8
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
59174488
Solubility/Reconstitution Instructions
DMSO (>50 mg/ml)
SMILES
COCCOC1=CC=C(C=C1)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)NC(=O)C=C)F
InChi
InChI=1S/C22H22FN5O3/c1-3-20(29)25-16-5-4-6-17(13-16)26-21-19(23)14-24-22(28-21)27-15-7-9-18(10-8-15)31-12-11-30-2/h3-10,13-14H,1,11-12H2,2H3,(H,25,29)(H2,24,26,27,28)
InChi Key
KXBDTLQSDKGAEB-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for AVL-292 (Spebrutinib) biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase InhibitorsEnzyme Inhibitors; Enzyme Inhibitors (A-Z) Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase InhibitorsBiochemicals; Enzyme Inhibitors; Enzym

Structure of AVL-292 (Spebrutinib) biochemical

AVL-292 (Spebrutinib) Biochemical – Cat# MBS841921

Other Notes

Small volumes of AVL-292 (Spebrutinib) biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AVL-292 (Spebrutinib) purchase

MBS841921 is a biochemical targeting AVL-292 (Spebrutinib).
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