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FIIN-2

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845757

FIIN-2 is a potent; selective; irreversible; next-generation covalent FGFR inhibitor. FIIN-2 is the first inhibitor that can potently inhibit the proliferation of cells dependent upon the gatekeeper mutants of FGFR1 or FGFR2; which confer resistance to… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
FIIN-2, Biochemical
Full Product Name
FIIN-2
Product Gene Name
FIIN-2 biochemical
Product Synonym Names
N- (4- ( (3- (3; 5-dimethoxyphenyl)-7- ( (4- (4-methylpiperazin-1-yl) phenyl) amino)-2-oxo-3; 4-dihydropyrimido[4; 5-d]pyrimidin-1 (2H)-yl) methyl) phenyl) acrylamide
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
634.73
Salt Form
No
CAS Number
1633044-56-0
Cell-Permeable
Yes
Reconstitution
DMSO >6 mg/ml)
SMILES
CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C4CN(C(=O)N(C4=N3)CC5=CC=C(C=C5)NC(=O)C=C)C6=CC(=CC(=C6)OC)OC
InChi
InChI=1S/C35H38N8O4/c1-5-32(44)37-26-8-6-24(7-9-26)22-43-33-25(23-42(35(43)45)29-18-30(46-3)20-31(19-29)47-4)21-36-34(39-33)38-27-10-12-28(13-11-27)41-16-14-40(2)15-17-41/h5-13,18-21H,1,14-17,22-23H2,2-4H3,(H,37,44)(H,36,38,39)
InChi Key
DVBPRWJMHURKHP-UHFFFAOYSA-N

Structure of FIIN-2 biochemical

FIIN-2 Biochemical – Cat# MBS845757

Other Notes

Small volumes of FIIN-2 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FIIN-2 purchase

MBS845757 is a biochemical targeting FIIN-2.
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