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Simeprevir ((2R)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846316

Simeprevir is a potent inhibitor of HCV NS3/4A protease with Ki value of 0.36 nM. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Simeprevir, Biochemical
Full Product Name
Simeprevir
Product Synonym Names
(2R; 3aR; 10Z; 11aS; 12aR; 14aR)-N- (Cyclopropylsulfonyl)-2; 3; 3a; 4; 5; 6; 7; 8; 9; 11a; 12; 13; 14; 14a-tetradecahydro-2-[[7-methoxy-8-methyl-2-[4- (1-methylethyl)-2-thiazolyl]-4-quinolinyl]oxy]-5-methyl-4; 14-dioxo-cyclopenta[c]cyclopropa[g][1; 6]diazacyclotetradecine-12a (1H)-carboxamide; TMC 435; TMC 435350
Form/Format
Off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
749.96
CAS Number
923604-59-5
Cell-Permeable
Yes
Reconstitution
DMSO
SMILES
CC1=C(C=CC2=C1N=C(C=C2OC3CC4C(C3)C(=O)N(CCCCC=CC5CC5(NC4=O)C(=O)NS(=O)(=O)C6CC6)C)C7=NC(=CS7)C(C)C)OC
InChi
InChI=1S/C38H47N5O7S2/c1-21(2)30-20-51-35(40-30)29-18-32(26-13-14-31(49-5)22(3)33(26)39-29)50-24-16-27-28(17-24)36(45)43(4)15-9-7-6-8-10-23-19-38(23,41-34(27)44)37(46)42-52(47,48)25-11-12-25/h8,10,13-14,18,20-21,23-25,27-28H,6-7,9,11-12,15-17,19H2,1-5H3,(H,41,44)(H,42,46)/b10-8-/t23-,24-,27-,28-,38-/m1/s1
InChi Key
JTZZSQYMACOLNN-VDWJNHBNSA-N

Structure of Simeprevir biochemical

Simeprevir (2R Biochemical – Cat# MBS846316

Other Notes

Small volumes of Simeprevir biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Simeprevir purchase

MBS846316 is a biochemical targeting Simeprevir.
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