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LY2228820

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848061

LY2228820 is a novel and potent inhibitor of p38 MAPK with IC50 of 7 nM in a cell-free assay, but does not alter p38 MAPK activation. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
LY2228820, Biochemical
Full Product Name
LY2228820
Product Synonym Names
LY2228820; LY 2228820; LY-2228820; LY2228820 dimesylate; Ralimetinib dimesylate; 5- (2- (tert-butyl)-4- (4-fluorophenyl)-1H-imidazol-5-yl)-3-neopentyl-3H-imidazo[4; 5-b]pyridin-2-amine dimethanesulfonate; 5-[2-tert-butyl-4- (4-fluorophenyl)-1H-imidazol-5-yl]-3- (2; 2-dimethylpropyl) imidazo[4; 5-b]pyridin-2-amine; methanesulfonic acid
Form/Format
Solid powder
Purity/Purification
>98%
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
612.74
Solubility
DMSO
Molecular Formula
C??H??FN?O?S?
CAS Number
862507-23-1
MDL Number
MFCD28101032
PubChem CID
11570805
SMILES
CC (C)(C)CN1C2=C (C=CC (=N2)C3=C (N=C (N3)C (C)(C)C)C4=CC=C (C=C4)F)N=C1N.CS (=O)(=O)O.CS (=O)(=O)O
InChi
InChI=1S/C24H29FN6.2CH4O3S/c1-23 (2,3)13-31-20-17 (28-22 (31)26)12-11-16 (27-20)19-18 (14-7-9-15 (25)10-8-14)29-21 (30-19)24 (4,5)6;2*1-5 (2,3)4/h7-12H,13H2,1-6H3, (H2,26,28)(H,29,30);2*1H3, (H,2,3,4)
InChi Key
NARMJPIBAXVUIE-UHFFFAOYSA-N

Product Categories/Family for LY2228820 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; MAP Kinase; MEK Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z)

Structure of LY2228820 biochemical

LY2228820 Biochemical – Cat# MBS848061

Product References and Citations for LY2228820 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/11570805#section=Top

Other Notes

Small volumes of LY2228820 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LY2228820 purchase

MBS848061 is a biochemical targeting LY2228820.
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