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PF-06409577

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS848326

PF-06409577 is a potent and selective allosteric activator of AMPK (EC50 values are 7 and >40000 nM for AMPKalpha1beta1gamma1 and AMPKalpha1beta2gamma1, respectively). Displays minimal off-target effects on a panel of receptors, ion channels, PDEs and… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PF-06409577, Biochemical
Full Product Name
PF-06409577
Product Synonym Names
6-Chloro-5-[4- (1-hydroxycyclobutyl) phenyl]-1H-indole-3-carboxylic acid
Form/Format
Off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C
Protect from air and light
Shelf life: ~36 months
Molecular Weight
341.79
Solubility
DMSO (>40 mg/ml)
Molecular Formula
C??H??ClNO?
CAS Number
1467057-23-3
PubChem CID
71748255
SMILES
C1CC (C1)(C2=CC=C (C=C2)C3=C (C=C4C (=C3)C (=CN4)C (=O)O)Cl)O
InChi
InChI=1S/C19H16ClNO3/c20-16-9-17-14 (15 (10-21-17)18 (22)23)8-13 (16)11-2-4-12 (5-3-11)19 (24)6-1-7-19/h2-5,8-10,21,24H,1,6-7H2, (H,22,23)
InChi Key
FHQXLWCFSUSXBF-UHFFFAOYSA-N

Product Categories/Family for PF-06409577 biochemical

Signaling Pathways; AMPK; Insulin; Leptin Signaling; AMPK Activators; Biochemicals; Biochemicals (A-Z)

Structure of PF-06409577 biochemical

Pf-06409577 Biochemical – Cat# MBS848326

Product References and Citations for PF-06409577 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/71748255

Other Notes

Small volumes of PF-06409577 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-06409577 purchase

MBS848326 is a biochemical targeting PF-06409577.
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