Rabbit Anti-PARD6B Antibody – Cat# MBS9125018

Western blot analysis of extracts of various cell lines, using PARD6B antibody (MBS9125018) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 5s.

PARD6B Antibody – Rabbit

Name: PARD6B Antibody; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS9125018
Price: 225 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9125018

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discslarge/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PARD6B, Antibody

Full Product Name

PARD6B Polyclonal Antibody

Product Gene Name

anti-PARD6B antibody

Product Synonym Names

PARD6B; PAR6B

Isotype

IgG

Host

Rabbit

Form/Format

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Purity/Purification

Affinity purification

Preparation and Storage

Store at -20°C. Avoid freeze / thaw cycles

Molecular Weight

Observed MW: 41kDa
Calculated MW: 12kDa/41kDa

OMIM

608975

3D Structure

ModBase 3D Structure for Q9BYG5

Species Reactivity/
Cross-Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 253-372 of human PARD6B (NP_115910.1).

Product Categories/Family for anti-PARD6B antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-PARD6B antibody

Western Blot (WB)

Application Notes for anti-PARD6B antibody

WB: 1:1000 - 1:4000

Other Notes

Small volumes of anti-PARD6B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PARD6B purchase

MBS9125018 is an antibody targeting PARD6B. Also known as PARD6B Polyclonal Antibody. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PARD6B. It may not necessarily be applicable to this product.

NCBI GI #

30913176

NCBI GeneID

84612

NCBI Accession #

Q9BYG5.1

UniProt Primary Accession #

Q9BYG5

UniProt Secondary Accession #

Q9Y510; A2A2A7

UniProt Related Accession #

Q9BYG5

NCBI Official Full Name

Partitioning defective 6 homolog beta

NCBI Official Synonym Full Names

par-6 family cell polarity regulator beta

NCBI Official Symbol

PARD6B

NCBI Official Synonym Symbols

PAR6B

UniProt Protein Name

Partitioning defective 6 homolog beta

Protein Family

Partitioning defective

UniProt Gene Name

PARD6B

UniProt Synonym Gene Names

PAR6B; PAR-6 beta; PAR-6B

UniProt Entry Name

PAR6B_HUMAN

NCBI Protein Information

partitioning defective 6 homolog beta; PAR-6 beta; par-6 partitioning defective 6 homolog beta

NCBI Summary for PARD6B

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. [provided by RefSeq, Jul 2008]

UniProt Comments for PARD6B

PARD6B: Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Belongs to the PAR6 family.

Protein type: Cell adhesion

Chromosomal Location of Human Ortholog: 20q13.13

Cellular Component: protein complex; tight junction; apical part of cell; cytoplasm; plasma membrane; cell cortex; nucleus; cytosol

Molecular Function: protein binding

Biological Process: intercellular junction assembly; intercellular junction assembly and maintenance; axonogenesis; cell division; establishment and/or maintenance of cell polarity; protein complex assembly; cell cycle; regulation of cell migration

Research Articles on PARD6B

1. Data conclude that Par6B and aPKC control mitotic spindle orientation in polarized epithelia and, furthermore, that aPKC coordinately regulates multiple processes to promote morphogenesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PARD6B antibody

Reference Product	PubMed Publications
PRKCZ antibody	>2 publications with PARD6B and PRKCZ
PARD6A antibody	>2 publications with PARD6B and PARD6A
PARD6G antibody	>1 publications with PARD6B and PARD6G
PARD3 antibody	>1 publications with PARD6B and PARD3
CDC42 antibody	>1 publications with PARD6B and CDC42

Pathways associated with anti-PARD6B antibody

Products by Pathway	Pathway Diagram
Cell Junction Organization Pathway antibodies	Cell Junction Organization Pathway Diagram
Cell-Cell Communication Pathway antibodies	Cell-Cell Communication Pathway Diagram
Cell-cell Junction Organization Pathway antibodies	Cell-cell Junction Organization Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram
Hippo Signaling Pathway antibodies	Hippo Signaling Pathway Diagram
Hippo Signaling Pathway antibodies	Hippo Signaling Pathway Diagram
Rap1 Signaling Pathway antibodies	Rap1 Signaling Pathway Diagram
Rap1 Signaling Pathway antibodies	Rap1 Signaling Pathway Diagram
Tight Junction Pathway antibodies	Tight Junction Pathway Diagram

Diseases associated with anti-PARD6B antibody

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>1 publications with PARD6B and Breast Neoplasms

Organs/Tissues associated with anti-PARD6B antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>2 publications with PARD6B and Brain
Thyroid Antibodies	>1 publications with PARD6B and Thyroid
Embryonic Tissue Antibodies	>1 publications with PARD6B and Embryonic Tissue
Intestine Antibodies	>1 publications with PARD6B and Intestine