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BI-2852

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3613732

BI-2852 is a KRAS inhibitor for the switch I/II pocket (SI/II-pocket) with nanomolar affinity. More details

$400 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BI-2852, Biochemical
Full Product Name
BI-2852
Product Gene Name
BI-2852 biochemical
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >= 2 years
Molecular Weight
516.59
Receptor
KRAS G12C
Solubility
DMSO: 55ug/mL (106.47mM; Need ultrasonic)
SMILES
Cn1cnc(Cn(cc2)c3c2ccc(CNCc2c([C@H](c4c5ccc(O)c4)NC5=O)c(cccc4)c4[nH]2)c3)c1
Molecular Formula
C31H28N6O2
CAS Number
2375482-51-0

Product Categories/Family for BI-2852 biochemical

Ras; MAPK/ERK Signaling

Chemical Structure of BI-2852 biochemical

BI-2852 Biochemical – Cat# MBS3613732

Product References and Citations for BI-2852 biochemical

1.Kessler D, et al. Drugging an undruggable pocket on KRAS. Proc Natl Acad Sci U S A. 2019 Aug 6; 116(32):15823-15829.

Other Notes

Small volumes of BI-2852 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BI-2852 purchase

MBS3613732 is a biochemical targeting BI-2852.
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